Post-ERCP Pancreatitis: Prevention, Diagnosis and Management

Endoscopic retrograde cholangiopancreatography (ERCP) carries a post-ERCP pancreatitis (PEP) rate of 2–10%, which could be as high as 30–50% in high-risk cases. PEP is severe in up to 5% of cases, with potential for life-threatening complications, including multi-organ failure, peripancreatic fluid...

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Main Authors: Oscar Cahyadi, Nadeem Tehami, Enrique de-Madaria, Keith Siau
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Medicina
Subjects:
Online Access:https://www.mdpi.com/1648-9144/58/9/1261
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author Oscar Cahyadi
Nadeem Tehami
Enrique de-Madaria
Keith Siau
author_facet Oscar Cahyadi
Nadeem Tehami
Enrique de-Madaria
Keith Siau
author_sort Oscar Cahyadi
collection DOAJ
description Endoscopic retrograde cholangiopancreatography (ERCP) carries a post-ERCP pancreatitis (PEP) rate of 2–10%, which could be as high as 30–50% in high-risk cases. PEP is severe in up to 5% of cases, with potential for life-threatening complications, including multi-organ failure, peripancreatic fluid collections, and death in up to 1% of cases. The risk of PEP is potentially predictable and may be modified with pharmacological measures and endoscopist technique. This review covers the definition, epidemiology and risk factors for PEP, with a focus on the latest evidence-based medical and endoscopic strategies to prevent and manage PEP.
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spelling doaj.art-bab34eef5a2c41ada544e365c245c9182023-11-23T17:40:38ZengMDPI AGMedicina1010-660X1648-91442022-09-01589126110.3390/medicina58091261Post-ERCP Pancreatitis: Prevention, Diagnosis and ManagementOscar Cahyadi0Nadeem Tehami1Enrique de-Madaria2Keith Siau3St. Josef-Hospital, A Hospital of the Ruhr-University Bochum, 44791 Bochum, GermanyDepartment of Gastroenterology, University Hospital Southampton NHS Foundation Trust, Southampton SO16 6YD, UKDepartment of Gastroenterology, Dr. Balmis General University Hospital and Department of Clinical Medicine, Miguel Hernández University, 03010 Alicante, SpainDepartment of Gastroenterology, Royal Cornwall Hospitals NHS Trust, Truro TR1 3LJ, UKEndoscopic retrograde cholangiopancreatography (ERCP) carries a post-ERCP pancreatitis (PEP) rate of 2–10%, which could be as high as 30–50% in high-risk cases. PEP is severe in up to 5% of cases, with potential for life-threatening complications, including multi-organ failure, peripancreatic fluid collections, and death in up to 1% of cases. The risk of PEP is potentially predictable and may be modified with pharmacological measures and endoscopist technique. This review covers the definition, epidemiology and risk factors for PEP, with a focus on the latest evidence-based medical and endoscopic strategies to prevent and manage PEP.https://www.mdpi.com/1648-9144/58/9/1261post-ERCP pancreatitisERCPpancreatic stentingnon-steroidal anti-inflammatory drugs
spellingShingle Oscar Cahyadi
Nadeem Tehami
Enrique de-Madaria
Keith Siau
Post-ERCP Pancreatitis: Prevention, Diagnosis and Management
Medicina
post-ERCP pancreatitis
ERCP
pancreatic stenting
non-steroidal anti-inflammatory drugs
title Post-ERCP Pancreatitis: Prevention, Diagnosis and Management
title_full Post-ERCP Pancreatitis: Prevention, Diagnosis and Management
title_fullStr Post-ERCP Pancreatitis: Prevention, Diagnosis and Management
title_full_unstemmed Post-ERCP Pancreatitis: Prevention, Diagnosis and Management
title_short Post-ERCP Pancreatitis: Prevention, Diagnosis and Management
title_sort post ercp pancreatitis prevention diagnosis and management
topic post-ERCP pancreatitis
ERCP
pancreatic stenting
non-steroidal anti-inflammatory drugs
url https://www.mdpi.com/1648-9144/58/9/1261
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AT keithsiau postercppancreatitispreventiondiagnosisandmanagement