Recent Advances in Total Synthesis of Strychnine (2017-2022)

Known for the complexity of its structure, strychnine remains to be one of the challenging targets of total synthesis. Generations of chemists have contributed to the total synthesis of strychnine since Woodward’s groundbreaking synthesis. Today, new strategies and tactics are still emerging for the...

Full description

Bibliographic Details
Main Author: Hua Yunkai
Format: Article
Language:English
Published: EDP Sciences 2022-01-01
Series:BIO Web of Conferences
Subjects:
Online Access:https://www.bio-conferences.org/articles/bioconf/pdf/2022/14/bioconf_fbse2022_01008.pdf
_version_ 1811178325987557376
author Hua Yunkai
author_facet Hua Yunkai
author_sort Hua Yunkai
collection DOAJ
description Known for the complexity of its structure, strychnine remains to be one of the challenging targets of total synthesis. Generations of chemists have contributed to the total synthesis of strychnine since Woodward’s groundbreaking synthesis. Today, new strategies and tactics are still emerging for the optimization of the route of strychnine synthesis. In this review, I discuss the documents about strychnine synthesis in the past five years with the aim of demonstrating the trend of the strategy and tactics of total synthesis.
first_indexed 2024-04-11T06:16:44Z
format Article
id doaj.art-bab5bcd7533745acb2728ccc8e231212
institution Directory Open Access Journal
issn 2117-4458
language English
last_indexed 2024-04-11T06:16:44Z
publishDate 2022-01-01
publisher EDP Sciences
record_format Article
series BIO Web of Conferences
spelling doaj.art-bab5bcd7533745acb2728ccc8e2312122022-12-22T04:41:02ZengEDP SciencesBIO Web of Conferences2117-44582022-01-01550100810.1051/bioconf/20225501008bioconf_fbse2022_01008Recent Advances in Total Synthesis of Strychnine (2017-2022)Hua Yunkai0Fudan University ShanghaiKnown for the complexity of its structure, strychnine remains to be one of the challenging targets of total synthesis. Generations of chemists have contributed to the total synthesis of strychnine since Woodward’s groundbreaking synthesis. Today, new strategies and tactics are still emerging for the optimization of the route of strychnine synthesis. In this review, I discuss the documents about strychnine synthesis in the past five years with the aim of demonstrating the trend of the strategy and tactics of total synthesis.https://www.bio-conferences.org/articles/bioconf/pdf/2022/14/bioconf_fbse2022_01008.pdfnatural productsstrychninesynthesis strategytotal synthesis
spellingShingle Hua Yunkai
Recent Advances in Total Synthesis of Strychnine (2017-2022)
BIO Web of Conferences
natural products
strychnine
synthesis strategy
total synthesis
title Recent Advances in Total Synthesis of Strychnine (2017-2022)
title_full Recent Advances in Total Synthesis of Strychnine (2017-2022)
title_fullStr Recent Advances in Total Synthesis of Strychnine (2017-2022)
title_full_unstemmed Recent Advances in Total Synthesis of Strychnine (2017-2022)
title_short Recent Advances in Total Synthesis of Strychnine (2017-2022)
title_sort recent advances in total synthesis of strychnine 2017 2022
topic natural products
strychnine
synthesis strategy
total synthesis
url https://www.bio-conferences.org/articles/bioconf/pdf/2022/14/bioconf_fbse2022_01008.pdf
work_keys_str_mv AT huayunkai recentadvancesintotalsynthesisofstrychnine20172022