Neurobiology of bipolar disorders: a review of genetic components, signaling pathways, biochemical changes, and neuroimaging findings

Neurobiology of bipolar disorders: a review of genetic components, signaling pathways, biochemical changes, and neuroimaging findings

Bipolar disorder (BD) is a chronic mental illness characterized by changes in mood that alternate between mania and hypomania or between depression and mixed states, often associated with functional impairment. Although effective pharmacological and non-pharmacological treatments are available, seve...

Full description

Bibliographic Details
Main Authors:	Giselli Scaini, Samira S. Valvassori, Alexandre P. Diaz, Camila N. Lima, Deborah Benevenuto, Gabriel R. Fries, Joao Quevedo
Format:	Article
Language:	English
Published:	Associação Brasileira de Psiquiatria (ABP) 2020-04-01
Series:	Brazilian Journal of Psychiatry
Subjects:	Bipolar disorder mania depression genetics epigenetics neurotrophins mitochondrial dysfunction oxidative stress inflammation hypothalamic-pituitary-adrenal axis circadian rhythm neuroimaging
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462020000500536&tlng=en

Similar Items

Neurobiological correlates of burnout
by: Durva Balkrishna Sail, et al.
Published: (2021-01-01)

Neuroimaging perspective in targeted treatment for type 2 diabetes melitus and sleep disorders
by: Karen M. von Deneen, et al.
Published: (2022-11-01)

The ACTH axis : pathogenesis, diagnosis, and treatment /
by: Gaillard, Rolf C.
Published: (2003)

Clinical Value of Inflammatory and Neurotrophic Biomarkers in Bipolar Disorder: A Systematic Review and Meta-Analysis
by: Amanda Vega-Núñez, et al.
Published: (2022-06-01)

Hypothalamic‐pituitary‐adrenal axis differentially responses to morning and evening psychological stress in healthy subjects
by: Yujiro Yamanaka, et al.
Published: (2019-03-01)

The Local Neuropeptide System of Keratinocytes
by: Nicola Cirillo
Published: (2021-12-01)

Estrogenic Action in Stress-Induced Neuroendocrine Regulation of Energy Homeostasis
by: Kristen N. Krolick, et al.
Published: (2022-03-01)

Chronic Stress in Bipolar Disorders Across the Different Clinical States: Roles of HPA Axis and Personality
by: Zhang M, et al.
Published: (2022-08-01)

Melatonin Secretion in Regulating the Circadian Rhythms of Reproduction in Goose (<i>Anser cygnoides</i>)
by: Qiang Bao, et al.
Published: (2023-08-01)

Influences of the stress endocrine system on the reproductive endocrine axis in sheep (Ovis aries)
by: Edward Narayan, et al.
Published: (2017-10-01)

Epigenetic signature of chronic maternal stress load during pregnancy might be a potential biomarker for spontaneous preterm birth
by: Rogac M, et al.
Published: (2018-12-01)

Genetic basis of depressive disorders
by: Yu. D. Davydova, et al.
Published: (2019-07-01)

NANOPARTICULATE BDNF AS A POTENTIAL ANTIDEPRESSANT VIA NEUROENDOCRINE MECHANISMS IN EXPERIMENTAL MODEL OF DEPRESSION
by: N.A.D. BINTI RAZLAN, et al.
Published: (2024-09-01)

The Involvement of Hypothalamus–Pituitary–Adrenal (HPA) Axis in Suicide Risk
by: Isabella Berardelli, et al.
Published: (2020-09-01)

Copeptin Levels in Clinically Silent Multiple Sclerosis
by: İrem İlgezdi, et al.
Published: (2022-12-01)

Ghrelin stimulation by hypothalamic–pituitary–adrenal axis activation depends on increasing cortisol levels
by: S Gilad, et al.
Published: (2017-11-01)

Challenges and solutions to recruitment of neonates and children having cardiac surgery into a study using a novel sampling device
by: Terrie Walker-Smith, et al.
Published: (2022-06-01)

Biological Factors Underpinning Suicidal Behaviour: An Update
by: Maya N. Abou Chahla, et al.
Published: (2023-03-01)

Circadian glucocorticoids throughout development
by: Marianne Lehmann, et al.
Published: (2023-04-01)

Salivary testosterone and cortisol levels in borderline personality disorder before and after a 12-week group dialectical behavior therapy intervention
by: Tori Dyson, et al.
Published: (2023-07-01)

Cortisol Variations to Estimate the Physiological Stress Response in Horses at a Traditional Equestrian Event
by: Sergi Olvera-Maneu, et al.
Published: (2023-01-01)

Research Note: Sex difference in changes in heterophil to lymphocyte ratios in response to acute exposure of both corticosterone and cortisol in the Pekin duck
by: V. Tetel, et al.
Published: (2022-07-01)

A novel role of oxytocin: Oxytocin-induced well-being in humans
by: Etsuro Ito, et al.
Published: (2019-08-01)

Research progress in the correlation between chronic stress and ovarian dysfunction
by: WEI Liutong, et al.
Published: (2024-12-01)

Circadian, Reward, and Emotion Systems in Teens prospective longitudinal study: protocol overview of an integrative reward-circadian rhythm model of first onset of bipolar spectrum disorder in adolescence
by: Lauren B. Alloy, et al.
Published: (2023-08-01)

Efficacy of spironolactone as adjunctive therapy to sodium valproate in bipolar‐I disorder: A double‐blind, randomized, placebo‐controlled clinical trial
by: Atefeh Zandifar, et al.
Published: (2023-12-01)

Impact of the menstrual cycle phases and time of day on markers of stress: salivary α-amylase and secretory immunoglobulin A
by: Josey K. Walker, et al.
Published: (2025-12-01)

Gut microbiota composition and metabolic characteristics in patients with Craniopharyngioma
by: Chunhui Liu, et al.
Published: (2024-04-01)

The Influence of Light Wavelength on Human HPA Axis Rhythms: A Systematic Review
by: Isabella Robertson-Dixon, et al.
Published: (2023-09-01)

Imaging of pediatric pituitary endocrinopathies
by: Vikas Chaudhary, et al.
Published: (2012-01-01)

A Comparative Study of Pituitary Volume Variations in Mri in Acute Onset of Psychiatric Conditions
by: Brijesh Kumar Soni, et al.
Published: (2017-02-01)

Reversible central adrenal insufficiency in survivors of COVID-19: results from a 24-month longitudinal study
by: Saroj Kumar Sahoo, et al.
Published: (2024-08-01)

Associations between adrenal gland volume and adipose tissue compartments – a whole body MRI study
by: Esther Askani, et al.
Published: (2024-07-01)

Epigenomic mechanisms of early adversity and HPA dysfunction: Considerations for PTSD research
by: Patrick O McGowan
Published: (2013-09-01)

Reversible suppression of hypothalamo–pituitary–adrenal axis in Addison’s disease due to ethinyl oestradiol-induced increase in total cortisol
by: Krzysztof C Lewandowski, et al.
Published: (2024-12-01)

Association between Temperament and Stress-related Gene Expression in Day-old Chickens
by: Akira Ishikawa, et al.
Published: (2024-08-01)

The impact of single‐dose trazodone administration on plasma endogenous adrenocorticotropic hormone and serum cortisol concentrations in healthy dogs
by: Morgan Brown, et al.
Published: (2024-01-01)

High rates of mood disorders in patients with chronic idiopathic eosinopenia
by: Eli Magen, et al.
Published: (2024-10-01)

THE EFFECT OF N-STEAROYLETHANOLAMINE ON THE STRESS HORMONES LEVELS IN OLD RATS WITH INDUCED CHRONIC INFLAMMATION
by: K.V. IBRAHIMOV, et al.
Published: (2024-04-01)

Interaction of chronic pain, obesity and time of day on cortisol in female human adolescents
by: Hershel Raff, et al.
Published: (2022-01-01)