Neurobiology of bipolar disorders: a review of genetic components, signaling pathways, biochemical changes, and neuroimaging findings

Neurobiology of bipolar disorders: a review of genetic components, signaling pathways, biochemical changes, and neuroimaging findings

Bipolar disorder (BD) is a chronic mental illness characterized by changes in mood that alternate between mania and hypomania or between depression and mixed states, often associated with functional impairment. Although effective pharmacological and non-pharmacological treatments are available, seve...

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Bibliographic Details
Main Authors:	Giselli Scaini, Samira S. Valvassori, Alexandre P. Diaz, Camila N. Lima, Deborah Benevenuto, Gabriel R. Fries, Joao Quevedo
Format:	Article
Language:	English
Published:	Associação Brasileira de Psiquiatria (ABP) 2020-04-01
Series:	Brazilian Journal of Psychiatry
Subjects:	Bipolar disorder mania depression genetics epigenetics neurotrophins mitochondrial dysfunction oxidative stress inflammation hypothalamic-pituitary-adrenal axis circadian rhythm neuroimaging
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462020000500536&tlng=en

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