Main Clinical and Laboratory Features of Children with Bacterial Meningitis: Experience from a Tertiary Paediatric Centre in Central Vietnam
Chau Duc Nguyen-Huu,1 Son Bui-Binh-Bao,1 Kiem Hao Tran,2 Van Tuan Mai,3 Diem Chi Nguyen-Thi,2 Hanh Chan Tran-Thi,2 Anh Nguyen-Duy-Nam,1 Phuc To,1 Van Anh Ton-Nu1 1Department of Pediatrics, Hue University of Medicine and Pharmacy, Hue University, Hue City, Vietnam; 2Pediatric Center, Hue Central Hosp...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2022-08-01
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| Series: | Pediatric Health, Medicine and Therapeutics |
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| Online Access: | https://www.dovepress.com/main-clinical-and-laboratory-features-of-children-with-bacterial-menin-peer-reviewed-fulltext-article-PHMT |
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| author | Nguyen-Huu CD Bui-Binh-Bao S Tran KH Mai VT Nguyen-Thi DC Tran-Thi HC Nguyen-Duy-Nam A To P Ton-Nu VA |
| author_facet | Nguyen-Huu CD Bui-Binh-Bao S Tran KH Mai VT Nguyen-Thi DC Tran-Thi HC Nguyen-Duy-Nam A To P Ton-Nu VA |
| author_sort | Nguyen-Huu CD |
| collection | DOAJ |
| description | Chau Duc Nguyen-Huu,1 Son Bui-Binh-Bao,1 Kiem Hao Tran,2 Van Tuan Mai,3 Diem Chi Nguyen-Thi,2 Hanh Chan Tran-Thi,2 Anh Nguyen-Duy-Nam,1 Phuc To,1 Van Anh Ton-Nu1 1Department of Pediatrics, Hue University of Medicine and Pharmacy, Hue University, Hue City, Vietnam; 2Pediatric Center, Hue Central Hospital, Hue City, Vietnam; 3Microbiology Department, Hue Central Hospital, Hue City, VietnamCorrespondence: Van Anh Ton-Nu, Department of Pediatrics, Hue University of Medicine and Pharmacy, Hue University, 06 Ngo Quyen St, Hue City, 49000, Vietnam, Tel +84 234 3822173, Fax +84 234 3826269, Email tnvananh@hueuni.edu.vnObjective: Our study aimed to summarize symptoms and laboratory findings of bacterial meningitis at a Vietnam tertiary care hospital.Methods: We performed a retrospective study and enrolled 33 children diagnosed with bacterial meningitis admitted at the Pediatric Center, Hue Central Hospital, between January 2019 and July 2021.Results: Only 24.2% (8 out of 33) cases can determine etiology of bacterial meningitis. Streptococcus pneumonia was the most common pathogen. The mortality in this study was 12.1%. The most commn symptoms were fever (93.9%) and vomiting (60.6%). Loss of consciousness and poor appetite were predominant among patients who died (75%); seizures and local paralysis accounted for a half. For cerebrospinal fluid (CSF), the cloudy or turbid color was the most common in bacterial meningitis (54.5%), CSF leucocytes in a half of patients were greater than 500 cells/mm3 (48.5%). CSF white blood cells count was higher among children who died.Conclusion: Streptococcus pneumonia was the most common pathogen. Fever, vomiting, loss of consciousness, local paralysis, and increased leucocytes, neutrophils of CSF were more common in severe cases.Keywords: bacterial meningitis, S. pneumonia, Vietnam, cerebrospinal fluid |
| first_indexed | 2024-04-13T00:06:08Z |
| format | Article |
| id | doaj.art-babc5dcf496f4e0aaa1ff53d3c72706d |
| institution | Directory Open Access Journal |
| issn | 1179-9927 |
| language | English |
| last_indexed | 2024-04-13T00:06:08Z |
| publishDate | 2022-08-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Pediatric Health, Medicine and Therapeutics |
| spelling | doaj.art-babc5dcf496f4e0aaa1ff53d3c72706d2022-12-22T03:11:14ZengDove Medical PressPediatric Health, Medicine and Therapeutics1179-99272022-08-01Volume 1328929577710Main Clinical and Laboratory Features of Children with Bacterial Meningitis: Experience from a Tertiary Paediatric Centre in Central VietnamNguyen-Huu CDBui-Binh-Bao STran KHMai VTNguyen-Thi DCTran-Thi HCNguyen-Duy-Nam ATo PTon-Nu VAChau Duc Nguyen-Huu,1 Son Bui-Binh-Bao,1 Kiem Hao Tran,2 Van Tuan Mai,3 Diem Chi Nguyen-Thi,2 Hanh Chan Tran-Thi,2 Anh Nguyen-Duy-Nam,1 Phuc To,1 Van Anh Ton-Nu1 1Department of Pediatrics, Hue University of Medicine and Pharmacy, Hue University, Hue City, Vietnam; 2Pediatric Center, Hue Central Hospital, Hue City, Vietnam; 3Microbiology Department, Hue Central Hospital, Hue City, VietnamCorrespondence: Van Anh Ton-Nu, Department of Pediatrics, Hue University of Medicine and Pharmacy, Hue University, 06 Ngo Quyen St, Hue City, 49000, Vietnam, Tel +84 234 3822173, Fax +84 234 3826269, Email tnvananh@hueuni.edu.vnObjective: Our study aimed to summarize symptoms and laboratory findings of bacterial meningitis at a Vietnam tertiary care hospital.Methods: We performed a retrospective study and enrolled 33 children diagnosed with bacterial meningitis admitted at the Pediatric Center, Hue Central Hospital, between January 2019 and July 2021.Results: Only 24.2% (8 out of 33) cases can determine etiology of bacterial meningitis. Streptococcus pneumonia was the most common pathogen. The mortality in this study was 12.1%. The most commn symptoms were fever (93.9%) and vomiting (60.6%). Loss of consciousness and poor appetite were predominant among patients who died (75%); seizures and local paralysis accounted for a half. For cerebrospinal fluid (CSF), the cloudy or turbid color was the most common in bacterial meningitis (54.5%), CSF leucocytes in a half of patients were greater than 500 cells/mm3 (48.5%). CSF white blood cells count was higher among children who died.Conclusion: Streptococcus pneumonia was the most common pathogen. Fever, vomiting, loss of consciousness, local paralysis, and increased leucocytes, neutrophils of CSF were more common in severe cases.Keywords: bacterial meningitis, S. pneumonia, Vietnam, cerebrospinal fluidhttps://www.dovepress.com/main-clinical-and-laboratory-features-of-children-with-bacterial-menin-peer-reviewed-fulltext-article-PHMTbacterial meningitiss. pneumoniavietnamcerebrospinal fluid |
| spellingShingle | Nguyen-Huu CD Bui-Binh-Bao S Tran KH Mai VT Nguyen-Thi DC Tran-Thi HC Nguyen-Duy-Nam A To P Ton-Nu VA Main Clinical and Laboratory Features of Children with Bacterial Meningitis: Experience from a Tertiary Paediatric Centre in Central Vietnam Pediatric Health, Medicine and Therapeutics bacterial meningitis s. pneumonia vietnam cerebrospinal fluid |
| title | Main Clinical and Laboratory Features of Children with Bacterial Meningitis: Experience from a Tertiary Paediatric Centre in Central Vietnam |
| title_full | Main Clinical and Laboratory Features of Children with Bacterial Meningitis: Experience from a Tertiary Paediatric Centre in Central Vietnam |
| title_fullStr | Main Clinical and Laboratory Features of Children with Bacterial Meningitis: Experience from a Tertiary Paediatric Centre in Central Vietnam |
| title_full_unstemmed | Main Clinical and Laboratory Features of Children with Bacterial Meningitis: Experience from a Tertiary Paediatric Centre in Central Vietnam |
| title_short | Main Clinical and Laboratory Features of Children with Bacterial Meningitis: Experience from a Tertiary Paediatric Centre in Central Vietnam |
| title_sort | main clinical and laboratory features of children with bacterial meningitis experience from a tertiary paediatric centre in central vietnam |
| topic | bacterial meningitis s. pneumonia vietnam cerebrospinal fluid |
| url | https://www.dovepress.com/main-clinical-and-laboratory-features-of-children-with-bacterial-menin-peer-reviewed-fulltext-article-PHMT |
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