Down-regulated miR-146a expression with increased neutrophil extracellular traps and apoptosis formation in autoimmune-mediated diffuse alveolar hemorrhage

Down-regulated miR-146a expression with increased neutrophil extracellular traps and apoptosis formation in autoimmune-mediated diffuse alveolar hemorrhage

Abstract Background Increasing evidences have suggested an important role of microRNAs (miRNAs) in regulating cell death processes including NETosis and apoptosis. Dysregulated expression of miRNAs and increased formation of neutrophil extracellular traps (NETs) and apoptosis participate in autoimmu...

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Bibliographic Details
Main Authors: Yu-Tung Hsieh, Yu-Chi Chou, Pin-Yu Kuo, Hung-Wen Tsai, Yi-Ting Yen, Ai-Li Shiau, Chrong-Reen Wang
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Journal of Biomedical Science
Subjects:
Diffuse alveolar hemorrhage
MiR-146a
TRAF6
Neutrophil extracellular trap
NETosis
Apoptosis
Online Access:https://doi.org/10.1186/s12929-022-00849-4

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