Long noncoding RNA MALAT1 inhibits the apoptosis and autophagy of hepatocellular carcinoma cell by targeting the microRNA-146a/PI3K/Akt/mTOR axis

Long noncoding RNA MALAT1 inhibits the apoptosis and autophagy of hepatocellular carcinoma cell by targeting the microRNA-146a/PI3K/Akt/mTOR axis

Abstract Background Increased long noncoding RNA (lncRNA) expression is characteristic to hepatocellular carcinoma (HCC) and several other neoplasms. The present study aimed to identify the mechanism underlying modulation of HCC development by the lncRNA metastasis-associated lung adenocarcinoma tra...

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Bibliographic Details
Main Authors: Ningfu Peng, Jingrong He, Jindu Li, Hao Huang, Weiqiao Huang, Yingyang Liao, Shaoliang Zhu
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Cancer Cell International
Subjects:
HCC
lncRNA
miR
PI3K
Apoptosis
Autophagy
Online Access:http://link.springer.com/article/10.1186/s12935-020-01231-w

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