Rechallenge in idiosyncratic drug-induced liver injury: An analysis of cases in two large prospective registries according to existing definitions

Rechallenge in idiosyncratic drug-induced liver injury: An analysis of cases in two large prospective registries according to existing definitions

Introduction: Data on positive rechallenge in idiosyncratic drug-induced liver injury (DILI) are scarce. We aim to analyse the clinical presentation, outcome and drugs associated with positive rechallenge in two DILI registries. Methods: Cases from the Spanish and Latin American DILI registries were...

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Bibliographic Details
Main Authors: J.M. Pinazo-Bandera, H. Niu, I. Alvarez-Alvarez, I. Medina-Cáliz, E. Del Campo-Herrera, A. Ortega-Alonso, M. Robles-Díaz, N. Hernández, R. Paraná, V. Nunes, M. Girala, F. Bessone, M.I. Lucena, R.J. Andrade, M. García Cortés
Format: Article
Language:English
Published: Elsevier 2024-05-01
Series:Pharmacological Research
Subjects:
Drug-induced liver injury
hepatotoxicity
positive rechallenge
acute liver failure
Online Access:http://www.sciencedirect.com/science/article/pii/S1043661824001270

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http://www.sciencedirect.com/science/article/pii/S1043661824001270

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