Aqueous Macrophages Contribute to Conserved CCL2 and CXCL10 Gradients in Uveitis

Aqueous Macrophages Contribute to Conserved CCL2 and CXCL10 Gradients in Uveitis

Purpose: Uveitis is a heterogenous group of inflammatory eye disease for which current cytokine-targeted immune therapies are effective for only a subset of patients. We hypothesized that despite pathophysiologic nuances that differentiate individual disease states, all forms of eye inflammation mig...

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Bibliographic Details
Main Authors: Joseph B. Lin, Kathryn L. Pepple, MD, PhD, Christian Concepcion, Yulia Korshunova, PhD, Michael A. Paley, MD, PhD, Grace L. Paley, MD, PhD, Jennifer Laurent, Rajendra S. Apte, MD, PhD, Lynn M. Hassman, MD, PhD
Format: Article
Language:English
Published: Elsevier 2024-07-01
Series:Ophthalmology Science
Subjects:
Chemokine
Cytokine
Macrophage
Single cell RNA sequencing
Uveitis
Online Access:http://www.sciencedirect.com/science/article/pii/S2666914523001859

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