COVID-19 vaccine acceptance in sub-Saharan African countries: A systematic review and meta-analysis
Vaccination is the most effective intervention for the primary prevention of COVID-19. Several studies have been conducted in sub-Saharan African countries on the acceptance and associated factors of COVID-19 vaccine. This review and meta-analysis aimed to recapitulate the pooled magnitude of vaccin...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-02-01
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| Series: | Heliyon |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S240584402300244X |
| _version_ | 1828000873961226240 |
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| author | Temesgen Worku Gudayu Hibist Tilahun Mengistie |
| author_facet | Temesgen Worku Gudayu Hibist Tilahun Mengistie |
| author_sort | Temesgen Worku Gudayu |
| collection | DOAJ |
| description | Vaccination is the most effective intervention for the primary prevention of COVID-19. Several studies have been conducted in sub-Saharan African countries on the acceptance and associated factors of COVID-19 vaccine. This review and meta-analysis aimed to recapitulate the pooled magnitude of vaccine acceptance and its favoring factors in sub-Saharan African countries. PUBMED, MEDLINE, Science Direct, Web of Science, and SCOPUS were the main databases searched from 15 March to 5 June 2022; and all the articles written in the English language were included. Also, some articles were retrieved from biomedical peer-reviewed journal sites and Google scholar. The quality of thirty-five selected articles was evaluated using an adapted scale for evaluating cross-sectional studies based on the Newcastle-Ottawa Scale. The result of the review and meta-analysis revealed that COVID-19 vaccine acceptance rate varied across studies. In a pooled analysis, factors such as; higher-level perception of infection risk (OR (95% CI (2.7 (2.1, 3.4))), perceived vaccine safety (13.9 (9.2, 20.9)), virus-related good knowledge (2.7 (2.3, 3.2)) and appropriate attitude (5.9 (4.4, 7.8)), adherence to safety precautions (5.5 (4.8, 6.2)), and infection experience (4.4 (2.8, 6.9)) were positively affected the COVID-19 vaccine acceptance. Also, vaccine acceptance was found to be high among males and chronically ill individuals. Thus, understanding factors that enhance vaccine acceptance would support planners to augment vaccine uptake in the region. |
| first_indexed | 2024-04-10T06:20:54Z |
| format | Article |
| id | doaj.art-bac34042480d45b2b348fdaf6e2cd903 |
| institution | Directory Open Access Journal |
| issn | 2405-8440 |
| language | English |
| last_indexed | 2024-04-10T06:20:54Z |
| publishDate | 2023-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj.art-bac34042480d45b2b348fdaf6e2cd9032023-03-02T04:59:55ZengElsevierHeliyon2405-84402023-02-0192e13037COVID-19 vaccine acceptance in sub-Saharan African countries: A systematic review and meta-analysisTemesgen Worku Gudayu0Hibist Tilahun Mengistie1Department of Clinical Midwifery, School of Midwifery, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia; Corresponding author.Merawi Primary Hospital, Amhara Regional Health Bureau, Amhara, EthiopiaVaccination is the most effective intervention for the primary prevention of COVID-19. Several studies have been conducted in sub-Saharan African countries on the acceptance and associated factors of COVID-19 vaccine. This review and meta-analysis aimed to recapitulate the pooled magnitude of vaccine acceptance and its favoring factors in sub-Saharan African countries. PUBMED, MEDLINE, Science Direct, Web of Science, and SCOPUS were the main databases searched from 15 March to 5 June 2022; and all the articles written in the English language were included. Also, some articles were retrieved from biomedical peer-reviewed journal sites and Google scholar. The quality of thirty-five selected articles was evaluated using an adapted scale for evaluating cross-sectional studies based on the Newcastle-Ottawa Scale. The result of the review and meta-analysis revealed that COVID-19 vaccine acceptance rate varied across studies. In a pooled analysis, factors such as; higher-level perception of infection risk (OR (95% CI (2.7 (2.1, 3.4))), perceived vaccine safety (13.9 (9.2, 20.9)), virus-related good knowledge (2.7 (2.3, 3.2)) and appropriate attitude (5.9 (4.4, 7.8)), adherence to safety precautions (5.5 (4.8, 6.2)), and infection experience (4.4 (2.8, 6.9)) were positively affected the COVID-19 vaccine acceptance. Also, vaccine acceptance was found to be high among males and chronically ill individuals. Thus, understanding factors that enhance vaccine acceptance would support planners to augment vaccine uptake in the region.http://www.sciencedirect.com/science/article/pii/S240584402300244XCOVID-19VaccineAcceptanceSub-SaharanAfricameta-Analysis |
| spellingShingle | Temesgen Worku Gudayu Hibist Tilahun Mengistie COVID-19 vaccine acceptance in sub-Saharan African countries: A systematic review and meta-analysis Heliyon COVID-19 Vaccine Acceptance Sub-Saharan Africa meta-Analysis |
| title | COVID-19 vaccine acceptance in sub-Saharan African countries: A systematic review and meta-analysis |
| title_full | COVID-19 vaccine acceptance in sub-Saharan African countries: A systematic review and meta-analysis |
| title_fullStr | COVID-19 vaccine acceptance in sub-Saharan African countries: A systematic review and meta-analysis |
| title_full_unstemmed | COVID-19 vaccine acceptance in sub-Saharan African countries: A systematic review and meta-analysis |
| title_short | COVID-19 vaccine acceptance in sub-Saharan African countries: A systematic review and meta-analysis |
| title_sort | covid 19 vaccine acceptance in sub saharan african countries a systematic review and meta analysis |
| topic | COVID-19 Vaccine Acceptance Sub-Saharan Africa meta-Analysis |
| url | http://www.sciencedirect.com/science/article/pii/S240584402300244X |
| work_keys_str_mv | AT temesgenworkugudayu covid19vaccineacceptanceinsubsaharanafricancountriesasystematicreviewandmetaanalysis AT hibisttilahunmengistie covid19vaccineacceptanceinsubsaharanafricancountriesasystematicreviewandmetaanalysis |