Determination of thiomersal and mercurial residues by photo-degradation and flow injection analysis with luminescence probing using carbon quantum dots prepared from thiourea
Thiomersal is an organomercurial compound but, despite that, it is widely used in vaccines formulations to inactivate organisms and toxins and to prevent microbial growth during storage and use. In this work, thiomersal (along with traces of mercurial residues) was determined after photo-degradation...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-08-01
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| Series: | Talanta Open |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S266683192300005X |
| _version_ | 1797811083280384000 |
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| author | Claudiomar R. Franco Jarol R. Miranda-Andrades Carlos A.T. Toloza Dunieskys G. Larrudé Luis Maqueira-Espinosa Ricardo Q. Aucelio Anna De Falco Marlin J. Pedrozo-Peñafiel |
| author_facet | Claudiomar R. Franco Jarol R. Miranda-Andrades Carlos A.T. Toloza Dunieskys G. Larrudé Luis Maqueira-Espinosa Ricardo Q. Aucelio Anna De Falco Marlin J. Pedrozo-Peñafiel |
| author_sort | Claudiomar R. Franco |
| collection | DOAJ |
| description | Thiomersal is an organomercurial compound but, despite that, it is widely used in vaccines formulations to inactivate organisms and toxins and to prevent microbial growth during storage and use. In this work, thiomersal (along with traces of mercurial residues) was determined after photo-degradation (using UV and H2O2) to produce Hg2+ that was determined by flow injection analysis using luminescence probing with carbon quantum dots (prepared from citric acid and thiourea). Linear analytical response was observed in the concentration range of 25 to 900 µg L−1 and the method was efficiently applied to the determination of thiomersal in vaccines against hepatitis B and diphtheria-tetanus with recoveries ranging from 93 to 94%. |
| first_indexed | 2024-03-13T07:17:23Z |
| format | Article |
| id | doaj.art-bacac0a9cb1b453495dbb343c670caf9 |
| institution | Directory Open Access Journal |
| issn | 2666-8319 |
| language | English |
| last_indexed | 2024-03-13T07:17:23Z |
| publishDate | 2023-08-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Talanta Open |
| spelling | doaj.art-bacac0a9cb1b453495dbb343c670caf92023-06-05T04:13:13ZengElsevierTalanta Open2666-83192023-08-017100184Determination of thiomersal and mercurial residues by photo-degradation and flow injection analysis with luminescence probing using carbon quantum dots prepared from thioureaClaudiomar R. Franco0Jarol R. Miranda-Andrades1Carlos A.T. Toloza2Dunieskys G. Larrudé3Luis Maqueira-Espinosa4Ricardo Q. Aucelio5Anna De Falco6Marlin J. Pedrozo-Peñafiel7Chemistry Department, Pontifícia Universidade Católica do Rio de Janeiro (PUC-Rio), Rio de Janeiro- RJ, BrazilChemistry Department, Pontifícia Universidade Católica do Rio de Janeiro (PUC-Rio), Rio de Janeiro- RJ, BrazilDepartment of Natural and Exact Sciences, Universidad de la Costa, Barranquilla, ColombiaEngineering School, Mackenzie Presbyterian University, São Paulo, BrazilChemistry Department, Pontifícia Universidade Católica do Rio de Janeiro (PUC-Rio), Rio de Janeiro- RJ, BrazilChemistry Department, Pontifícia Universidade Católica do Rio de Janeiro (PUC-Rio), Rio de Janeiro- RJ, Brazil; Correspondent author.Chemistry Department, Pontifícia Universidade Católica do Rio de Janeiro (PUC-Rio), Rio de Janeiro- RJ, BrazilChemistry Department, Pontifícia Universidade Católica do Rio de Janeiro (PUC-Rio), Rio de Janeiro- RJ, BrazilThiomersal is an organomercurial compound but, despite that, it is widely used in vaccines formulations to inactivate organisms and toxins and to prevent microbial growth during storage and use. In this work, thiomersal (along with traces of mercurial residues) was determined after photo-degradation (using UV and H2O2) to produce Hg2+ that was determined by flow injection analysis using luminescence probing with carbon quantum dots (prepared from citric acid and thiourea). Linear analytical response was observed in the concentration range of 25 to 900 µg L−1 and the method was efficiently applied to the determination of thiomersal in vaccines against hepatitis B and diphtheria-tetanus with recoveries ranging from 93 to 94%.http://www.sciencedirect.com/science/article/pii/S266683192300005XMercuryThiomersalVaccinesFlow injection analysisPhoto-degradationCarbon quantum dots |
| spellingShingle | Claudiomar R. Franco Jarol R. Miranda-Andrades Carlos A.T. Toloza Dunieskys G. Larrudé Luis Maqueira-Espinosa Ricardo Q. Aucelio Anna De Falco Marlin J. Pedrozo-Peñafiel Determination of thiomersal and mercurial residues by photo-degradation and flow injection analysis with luminescence probing using carbon quantum dots prepared from thiourea Talanta Open Mercury Thiomersal Vaccines Flow injection analysis Photo-degradation Carbon quantum dots |
| title | Determination of thiomersal and mercurial residues by photo-degradation and flow injection analysis with luminescence probing using carbon quantum dots prepared from thiourea |
| title_full | Determination of thiomersal and mercurial residues by photo-degradation and flow injection analysis with luminescence probing using carbon quantum dots prepared from thiourea |
| title_fullStr | Determination of thiomersal and mercurial residues by photo-degradation and flow injection analysis with luminescence probing using carbon quantum dots prepared from thiourea |
| title_full_unstemmed | Determination of thiomersal and mercurial residues by photo-degradation and flow injection analysis with luminescence probing using carbon quantum dots prepared from thiourea |
| title_short | Determination of thiomersal and mercurial residues by photo-degradation and flow injection analysis with luminescence probing using carbon quantum dots prepared from thiourea |
| title_sort | determination of thiomersal and mercurial residues by photo degradation and flow injection analysis with luminescence probing using carbon quantum dots prepared from thiourea |
| topic | Mercury Thiomersal Vaccines Flow injection analysis Photo-degradation Carbon quantum dots |
| url | http://www.sciencedirect.com/science/article/pii/S266683192300005X |
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