Enhanced Intradermal Delivery of Nanosuspensions of Antifilariasis Drugs Using Dissolving Microneedles: A Proof of Concept Study

Enhanced Intradermal Delivery of Nanosuspensions of Antifilariasis Drugs Using Dissolving Microneedles: A Proof of Concept Study

Conventional oral administration of antifilariasis drugs results in nonspecific targeting of the drugs and the intradermal delivery of nanoparticles with sizes of <100 nm could be used to improve lymphatic uptake. This study investigated the combination of nanosuspension and dissolving micron...

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Bibliographic Details
Main Authors:	Andi Dian Permana, Maelíosa T. C. McCrudden, Ryan F. Donnelly
Format:	Article
Language:	English
Published:	MDPI AG 2019-07-01
Series:	Pharmaceutics
Subjects:	doxycycline albendazole ivermectin nanosuspension microneedles dermatokinetic lymphatic filariasis
Online Access:	https://www.mdpi.com/1999-4923/11/7/346

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