Down-regulation of the tumour suppressor κ-opioid receptor predicts poor prognosis in hepatocellular carcinoma patients

Down-regulation of the tumour suppressor κ-opioid receptor predicts poor prognosis in hepatocellular carcinoma patients

Abstract Background Opioid receptors have become increasingly implicated in cancer progression and long-term patient outcomes. However, the expression and significance of the κ-opioid receptor (KOR) in hepatocellular carcinoma (HCC) remain unclear. Methods In this study, KOR mRNA expression was anal...

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Bibliographic Details
Main Authors: Dongtai Chen, Yonghua Chen, Yan Yan, Jiahao Pan, Wei Xing, Qiang Li, Weian Zeng
Format: Article
Language:English
Published: BMC 2017-08-01
Series:BMC Cancer
Subjects:
Hepatocellular carcinoma
κ-opioid receptor
Prognosis
Tumour suppressor
Online Access:http://link.springer.com/article/10.1186/s12885-017-3541-9

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