Paradigm shift in dendritic cell-based immunotherapy: from in vitro generated monocyte-derived DCs to naturally circulating DC subsets

Paradigm shift in dendritic cell-based immunotherapy: from in vitro generated monocyte-derived DCs to naturally circulating DC subsets

Dendritic cell-based immunotherapy employs the patients’ immune system to fight neoplastic lesions spread over the entire body. This makes it an important therapy option for patients suffering from metastatic melanoma, which is often resistant to chemotherapy. However, conventional cellular vaccinat...

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Bibliographic Details
Main Authors:	Florian eWimmers, Gerty eSchreibelt, Annette E. Sköld, Carl G. Figdor, I. Jolanda M. ede Vries
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2014-04-01
Series:	Frontiers in Immunology
Subjects:	Immunotherapy Melanoma plasmacytoid dendritic cells Monocyte-derived dendritic cells myeloid dendritic cells dendritic cell vaccination
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00165/full

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