Carbon dots enhance extracellular matrix secretion for dentin-pulp complex regeneration through PI3K/Akt/mTOR pathway-mediated activation of autophagy

Carbon dots enhance extracellular matrix secretion for dentin-pulp complex regeneration through PI3K/Akt/mTOR pathway-mediated activation of autophagy

Pulp injury is one of the most common clinical diseases, and severe cases are usually associated with the functional loss of the tooth, while the current clinical treatment modality is only a cavity filling procedure without the regeneration of the dentin-pulp complex, thus leading to a devitalized...

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Bibliographic Details
Main Authors: Lili Liu, Xianjing Li, Wenhuan Bu, Nianqiang Jin, Yuan Meng, Yi Wang, Duan Wang, Xiaowei Xu, Ding Zhou, Hongchen Sun
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Materials Today Bio
Subjects:
Carbon dots
Extracellular matrix
Dentin-pulp complex regeneration
Autophagy
PI3K/Akt/mTOR signaling pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006422001429

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