Neuroprotective effects of chloroquine on neurological scores, blood-brain barrier permeability, and brain edema after traumatic brain injury in male rats

Background Traumatic brain injury (TBI) is one of the leading causes of death among young people worldwide. Chloroquine, an antimalarial drug, has been shown to easily cross the blood-brain barrier (BBB) and inhibit autophagy in a variety of disorders, including Alzheimer disease and brain ischemia....

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Bibliographic Details
Main Authors: Maryam Karimi, Somayeh Nazari, Faramarz Shirani, Vahid Alivirdiloo, Ali Siahposht-Khachaki, Sepehr Edalatkhah, Rama Khanian
Format: Article
Language:English
Published: The Korean Neurocritical Care Society 2023-06-01
Series:Journal of Neurocritical Care
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Online Access:http://e-jnc.org/upload/pdf/jnc-220052.pdf