Metastatic Sebaceous Carcinoma Presenting as Cheek Nodule: A Rare Case

Sebaceous Carcinoma is a rare locally aggressive tumour of adnexal epithelium with a potential to metastasize to regional lymph node and distant organs. It constitutes between 1.5 to 5% of all eyelid malignant tumours. After basal cell and squamous cell carcinomas, it ranks third in incidence. Seb...

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Main Authors: Ayushi Saxena, Ashumi Gupta
Format: Article
Language:English
Published: JCDR Research and Publications Pvt. Ltd. 2022-01-01
Series:National Journal of Laboratory Medicine
Subjects:
Online Access:https://www.njlm.net/articles/PDF/2558/48938_CE[Ra1]_F(SHU)_GC(AnK)_PF1(AKA_SHU)_PN(SHU).pdf
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author Ayushi Saxena
Ashumi Gupta
author_facet Ayushi Saxena
Ashumi Gupta
author_sort Ayushi Saxena
collection DOAJ
description Sebaceous Carcinoma is a rare locally aggressive tumour of adnexal epithelium with a potential to metastasize to regional lymph node and distant organs. It constitutes between 1.5 to 5% of all eyelid malignant tumours. After basal cell and squamous cell carcinomas, it ranks third in incidence. Sebaceous carcinoma is seen more commonly in elderly females with average age at diagnosis in mid-sixties. Few cases have been reported in paediatric age group. Sebaceous Gland Carcinoma (SGC) is a slowly progressive tumor that arises usually from the meibomian gland in the eyelid, and has a locally aggressive nature with a tendency for pagetoid spread. The neoplasm is known to masquerade other benign and less malignant lesions. The non-specific clinical symptoms may lead to a delay in diagnosis of sebaceous carcinoma of the eyelid. Less than 120 cases of extra-occular sebaceous cell carcinoma have been reported so far. Here, the authors present a case of 60 years old female patient, who presented with cheek nodule and cytological diagnosis of metastatic sebaceous carcinoma was made based on cytomorphological features.
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spelling doaj.art-bad8dded37654f21a78b3afe36fd34c22022-12-21T21:17:43ZengJCDR Research and Publications Pvt. Ltd.National Journal of Laboratory Medicine2277-85512455-68822022-01-011101010310.7860/NJLM/2022/48938.2558Metastatic Sebaceous Carcinoma Presenting as Cheek Nodule: A Rare CaseAyushi Saxena0Ashumi Gupta1Senior Resident, Department of Pathology, Geetanjali Medical College and Hospital (GMCH), Udaipur, Rajasthan, IndiaAssociate Professor, Department of Pathology, Geetanjali Medical College and Hospital (GMCH), Udaipur, Rajasthan, India.Sebaceous Carcinoma is a rare locally aggressive tumour of adnexal epithelium with a potential to metastasize to regional lymph node and distant organs. It constitutes between 1.5 to 5% of all eyelid malignant tumours. After basal cell and squamous cell carcinomas, it ranks third in incidence. Sebaceous carcinoma is seen more commonly in elderly females with average age at diagnosis in mid-sixties. Few cases have been reported in paediatric age group. Sebaceous Gland Carcinoma (SGC) is a slowly progressive tumor that arises usually from the meibomian gland in the eyelid, and has a locally aggressive nature with a tendency for pagetoid spread. The neoplasm is known to masquerade other benign and less malignant lesions. The non-specific clinical symptoms may lead to a delay in diagnosis of sebaceous carcinoma of the eyelid. Less than 120 cases of extra-occular sebaceous cell carcinoma have been reported so far. Here, the authors present a case of 60 years old female patient, who presented with cheek nodule and cytological diagnosis of metastatic sebaceous carcinoma was made based on cytomorphological features.https://www.njlm.net/articles/PDF/2558/48938_CE[Ra1]_F(SHU)_GC(AnK)_PF1(AKA_SHU)_PN(SHU).pdfdistant organsfine needle aspiration cytologyocular sebaceous carcinoma
spellingShingle Ayushi Saxena
Ashumi Gupta
Metastatic Sebaceous Carcinoma Presenting as Cheek Nodule: A Rare Case
National Journal of Laboratory Medicine
distant organs
fine needle aspiration cytology
ocular sebaceous carcinoma
title Metastatic Sebaceous Carcinoma Presenting as Cheek Nodule: A Rare Case
title_full Metastatic Sebaceous Carcinoma Presenting as Cheek Nodule: A Rare Case
title_fullStr Metastatic Sebaceous Carcinoma Presenting as Cheek Nodule: A Rare Case
title_full_unstemmed Metastatic Sebaceous Carcinoma Presenting as Cheek Nodule: A Rare Case
title_short Metastatic Sebaceous Carcinoma Presenting as Cheek Nodule: A Rare Case
title_sort metastatic sebaceous carcinoma presenting as cheek nodule a rare case
topic distant organs
fine needle aspiration cytology
ocular sebaceous carcinoma
url https://www.njlm.net/articles/PDF/2558/48938_CE[Ra1]_F(SHU)_GC(AnK)_PF1(AKA_SHU)_PN(SHU).pdf
work_keys_str_mv AT ayushisaxena metastaticsebaceouscarcinomapresentingascheeknoduleararecase
AT ashumigupta metastaticsebaceouscarcinomapresentingascheeknoduleararecase