Control of the temporal development of Alzheimer’s disease pathology by the MR1/MAIT cell axis

Control of the temporal development of Alzheimer’s disease pathology by the MR1/MAIT cell axis

Abstract Background Neuroinflammation is an important feature of Alzheimer’s disease (AD). Understanding which aspects of the immune system are important in AD may lead to new therapeutic approaches. We study the major histocompatibility complex class I-related immune molecule, MR1, which is recogni...

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Bibliographic Details
Main Authors: Season K. Wyatt-Johnson, Holly N. Kersey, Juan F. Codocedo, Kathy L. Newell, Gary E. Landreth, Bruce T. Lamb, Adrian L. Oblak, Randy R. Brutkiewicz
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Journal of Neuroinflammation
Subjects:
Amyloid
Innate immunity
T cell activation
Mouse models
Alzheimer’s disease
Online Access:https://doi.org/10.1186/s12974-023-02761-6

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