Beware of the Acute Respiratory Distress Syndrome in a Pulmonary Blastomycosis!
Blastomyces dermatitidis is a dimorphic fungus that can range from mild to severe disease presentation, including the acute respiratory distress syndrome (ARDS) based on the individual’s immunity. Acute respiratory distress syndrome is an uncommon presentation having an incidence of about 10% to 15%...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2024-02-01
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| Series: | Journal of Investigative Medicine High Impact Case Reports |
| Online Access: | https://doi.org/10.1177/23247096241233042 |
| _version_ | 1797301953294761984 |
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| author | Avinash Vangara MD Dedeepya Gullapalli MD Jayaram Krishna Depa MD Sandhya Kolagatla MD Muhammad Ali MD Subramanya Shyam Ganti MD, FCCP |
| author_facet | Avinash Vangara MD Dedeepya Gullapalli MD Jayaram Krishna Depa MD Sandhya Kolagatla MD Muhammad Ali MD Subramanya Shyam Ganti MD, FCCP |
| author_sort | Avinash Vangara MD |
| collection | DOAJ |
| description | Blastomyces dermatitidis is a dimorphic fungus that can range from mild to severe disease presentation, including the acute respiratory distress syndrome (ARDS) based on the individual’s immunity. Acute respiratory distress syndrome is an uncommon presentation having an incidence of about 10% to 15% but has a high mortality exceeding 90%. This is a case of a 50-year-old female with past medical history of asthma and type 2 diabetes mellitus who presented to the pulmonology clinic with worsening dyspnea for the last 2 months. She also had a lesion in the left lower back, which was draining purulent fluid. Chest radiographs showed bilateral infiltrates and was started empirically on vancomycin and piperacillin-tazobactam. Bronchoalveolar lavage was done and the cultures grew B dermatitidis. The patient was moved to a higher level of care and given amphotericin B. Unfortunately, the patient experienced septic shock, which later deteriorated into cardiac arrest, ultimately leading to their passing. The importance of early diagnosis of blastomycosis and timely treatment has been emphasized in this case report. |
| first_indexed | 2024-03-07T23:29:58Z |
| format | Article |
| id | doaj.art-badc0e93a715432aaa633231183cbc7d |
| institution | Directory Open Access Journal |
| issn | 2324-7096 |
| language | English |
| last_indexed | 2024-03-07T23:29:58Z |
| publishDate | 2024-02-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Journal of Investigative Medicine High Impact Case Reports |
| spelling | doaj.art-badc0e93a715432aaa633231183cbc7d2024-02-20T18:03:23ZengSAGE PublishingJournal of Investigative Medicine High Impact Case Reports2324-70962024-02-011210.1177/23247096241233042Beware of the Acute Respiratory Distress Syndrome in a Pulmonary Blastomycosis!Avinash Vangara MD0Dedeepya Gullapalli MD1Jayaram Krishna Depa MD2Sandhya Kolagatla MD3Muhammad Ali MD4Subramanya Shyam Ganti MD, FCCP5Internal Medicine Residency Program, Appalachian Regional Healthcare, Harlan, KY, USAInternal Medicine Residency Program, Appalachian Regional Healthcare, Harlan, KY, USAInternal Medicine Residency Program, Appalachian Regional Healthcare, Harlan, KY, USAInternal Medicine Residency Program, Appalachian Regional Healthcare, Whitesburg, KY, USAAppalachian Regional Hospital, Hazard, KY, USAInternal Medicine Residency Program, Appalachian Regional Healthcare, Harlan, KY, USABlastomyces dermatitidis is a dimorphic fungus that can range from mild to severe disease presentation, including the acute respiratory distress syndrome (ARDS) based on the individual’s immunity. Acute respiratory distress syndrome is an uncommon presentation having an incidence of about 10% to 15% but has a high mortality exceeding 90%. This is a case of a 50-year-old female with past medical history of asthma and type 2 diabetes mellitus who presented to the pulmonology clinic with worsening dyspnea for the last 2 months. She also had a lesion in the left lower back, which was draining purulent fluid. Chest radiographs showed bilateral infiltrates and was started empirically on vancomycin and piperacillin-tazobactam. Bronchoalveolar lavage was done and the cultures grew B dermatitidis. The patient was moved to a higher level of care and given amphotericin B. Unfortunately, the patient experienced septic shock, which later deteriorated into cardiac arrest, ultimately leading to their passing. The importance of early diagnosis of blastomycosis and timely treatment has been emphasized in this case report.https://doi.org/10.1177/23247096241233042 |
| spellingShingle | Avinash Vangara MD Dedeepya Gullapalli MD Jayaram Krishna Depa MD Sandhya Kolagatla MD Muhammad Ali MD Subramanya Shyam Ganti MD, FCCP Beware of the Acute Respiratory Distress Syndrome in a Pulmonary Blastomycosis! Journal of Investigative Medicine High Impact Case Reports |
| title | Beware of the Acute Respiratory Distress Syndrome in a Pulmonary Blastomycosis! |
| title_full | Beware of the Acute Respiratory Distress Syndrome in a Pulmonary Blastomycosis! |
| title_fullStr | Beware of the Acute Respiratory Distress Syndrome in a Pulmonary Blastomycosis! |
| title_full_unstemmed | Beware of the Acute Respiratory Distress Syndrome in a Pulmonary Blastomycosis! |
| title_short | Beware of the Acute Respiratory Distress Syndrome in a Pulmonary Blastomycosis! |
| title_sort | beware of the acute respiratory distress syndrome in a pulmonary blastomycosis |
| url | https://doi.org/10.1177/23247096241233042 |
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