Effects of prior reproductive losses on risk of cardiovascular diseases within six months of a first live birth
Objective: There is emerging evidence suggesting that pregnancy loss (induced or natural) is associated with an increased risk of cardiovascular diseases (CVD). This prospective longitudinal study investigates the effect of prior pregnancy losses on CVD risk during the first six months following a f...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2024-06-01
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| Series: | International Journal of Cardiology. Cardiovascular Risk and Prevention |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772487524000254 |
| _version_ | 1797259661736411136 |
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| author | Maka Tsulukidze David C. Reardon Christopher Craver |
| author_facet | Maka Tsulukidze David C. Reardon Christopher Craver |
| author_sort | Maka Tsulukidze |
| collection | DOAJ |
| description | Objective: There is emerging evidence suggesting that pregnancy loss (induced or natural) is associated with an increased risk of cardiovascular diseases (CVD). This prospective longitudinal study investigates the effect of prior pregnancy losses on CVD risk during the first six months following a first live birth. Methods: Medicaid claims of 1,002,556 low-income women were examined to identify history of pregnancy losses, CVD, diabetes, and hyperlipidemia prior to first live birth. The study population was categorized into five groups: A: women with no pregnancy loss or CVD history prior to first live birth; B: women with pregnancy loss and no CVD prior to first live birth. C: women with a first CVD diagnosis after a first pregnancy ending in a loss and before their first live birth. D: women with CVD prior to first live birth and no history of pregnancy loss. E: women with both CVD and pregnancy loss prior to their first live birth. Results: After controlling for age, race, state of residence, and history of diabetes and hyperlipidemia, the risk of CVD in the six-month period following a first live birth were 15%, 214%, 79% and 129% more common for Groups B, C, D and E, respectively, compared to Group A. Conclusions: Pregnancy loss is an independent risk factor for CVD risk following a first live birth, both for women with and without a prior history of CVD. The risk is highest when CVD is first diagnosed after a pregnancy loss and prior to a first live birth. |
| first_indexed | 2024-04-24T23:12:59Z |
| format | Article |
| id | doaj.art-bae0681c707c4d82b7133ed419d34023 |
| institution | Directory Open Access Journal |
| issn | 2772-4875 |
| language | English |
| last_indexed | 2024-04-24T23:12:59Z |
| publishDate | 2024-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | International Journal of Cardiology. Cardiovascular Risk and Prevention |
| spelling | doaj.art-bae0681c707c4d82b7133ed419d340232024-03-17T07:59:15ZengElsevierInternational Journal of Cardiology. Cardiovascular Risk and Prevention2772-48752024-06-0121200260Effects of prior reproductive losses on risk of cardiovascular diseases within six months of a first live birthMaka Tsulukidze0David C. Reardon1Christopher Craver2Florida Gulf Coast University, Fort Myers, FL, USAElliot Institute, Gulf Breeze, FL, USA; Charlotte Lozier Institute, Arlington, VA, USA; Corresponding author. Gulf Breeze, FL USA.Charlotte Lozier Institute, Arlington, VA, USAObjective: There is emerging evidence suggesting that pregnancy loss (induced or natural) is associated with an increased risk of cardiovascular diseases (CVD). This prospective longitudinal study investigates the effect of prior pregnancy losses on CVD risk during the first six months following a first live birth. Methods: Medicaid claims of 1,002,556 low-income women were examined to identify history of pregnancy losses, CVD, diabetes, and hyperlipidemia prior to first live birth. The study population was categorized into five groups: A: women with no pregnancy loss or CVD history prior to first live birth; B: women with pregnancy loss and no CVD prior to first live birth. C: women with a first CVD diagnosis after a first pregnancy ending in a loss and before their first live birth. D: women with CVD prior to first live birth and no history of pregnancy loss. E: women with both CVD and pregnancy loss prior to their first live birth. Results: After controlling for age, race, state of residence, and history of diabetes and hyperlipidemia, the risk of CVD in the six-month period following a first live birth were 15%, 214%, 79% and 129% more common for Groups B, C, D and E, respectively, compared to Group A. Conclusions: Pregnancy loss is an independent risk factor for CVD risk following a first live birth, both for women with and without a prior history of CVD. The risk is highest when CVD is first diagnosed after a pregnancy loss and prior to a first live birth.http://www.sciencedirect.com/science/article/pii/S2772487524000254Cardiovascular diseasePregnancy lossPregnancy risk factorsRisk factorsInduced abortionMiscarriage |
| spellingShingle | Maka Tsulukidze David C. Reardon Christopher Craver Effects of prior reproductive losses on risk of cardiovascular diseases within six months of a first live birth International Journal of Cardiology. Cardiovascular Risk and Prevention Cardiovascular disease Pregnancy loss Pregnancy risk factors Risk factors Induced abortion Miscarriage |
| title | Effects of prior reproductive losses on risk of cardiovascular diseases within six months of a first live birth |
| title_full | Effects of prior reproductive losses on risk of cardiovascular diseases within six months of a first live birth |
| title_fullStr | Effects of prior reproductive losses on risk of cardiovascular diseases within six months of a first live birth |
| title_full_unstemmed | Effects of prior reproductive losses on risk of cardiovascular diseases within six months of a first live birth |
| title_short | Effects of prior reproductive losses on risk of cardiovascular diseases within six months of a first live birth |
| title_sort | effects of prior reproductive losses on risk of cardiovascular diseases within six months of a first live birth |
| topic | Cardiovascular disease Pregnancy loss Pregnancy risk factors Risk factors Induced abortion Miscarriage |
| url | http://www.sciencedirect.com/science/article/pii/S2772487524000254 |
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