First-in-Human Segmental Esophageal Reconstruction Using a Bioengineered Mesenchymal Stromal Cell–Seeded Implant

First-in-Human Segmental Esophageal Reconstruction Using a Bioengineered Mesenchymal Stromal Cell–Seeded Implant

Introduction: Resection and reconstruction of the esophagus remains fraught with morbidity and mortality. Recently, data from a porcine reconstruction model revealed that segmental esophageal reconstruction using an autologous mesenchymal stromal cell-seeded polyurethane graft (Cellspan esophageal i...

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Bibliographic Details
Main Authors: Johnathon M. Aho, MD, PhD, Saverio La Francesca, MD, Scott D. Olson, PhD, Fabio Triolo, PhD, Jeff Bouchard, BS, Laura Mondano, BS, Sumati Sundaram, PhD, Christina Roffidal, MPH, Charles S. Cox, Jr., MD, Louis M. Wong Kee Song, MD, Sameh M. Said, MB, BCh, MD, William Fodor, PhD, Dennis A. Wigle, MD, PhD
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:JTO Clinical and Research Reports
Subjects:
Esophageal reconstruction
Tissue engineered graft
Artificial organ
Esophageal replacement
Online Access:http://www.sciencedirect.com/science/article/pii/S2666364321000758

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