Healthy Aging in Menopause: Prevention of Cognitive Decline, Depression and Dementia through Physical Exercise

The aging of the global population is a significant and complex phenomenon with far-reaching implications for healthcare systems and society. By 2030, it is projected that the number of individuals over the age of 65 will increase by nearly 1 billion, largely due to advancements in healthcare and im...

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Main Authors: Carmen Guerrero-González, Cristina Cueto-Ureña, Vanesa Cantón-Habas, María Jesús Ramírez-Expósito, José Manuel Martínez-Martos
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Physiologia
Subjects:
Online Access:https://www.mdpi.com/2673-9488/4/1/7
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author Carmen Guerrero-González
Cristina Cueto-Ureña
Vanesa Cantón-Habas
María Jesús Ramírez-Expósito
José Manuel Martínez-Martos
author_facet Carmen Guerrero-González
Cristina Cueto-Ureña
Vanesa Cantón-Habas
María Jesús Ramírez-Expósito
José Manuel Martínez-Martos
author_sort Carmen Guerrero-González
collection DOAJ
description The aging of the global population is a significant and complex phenomenon with far-reaching implications for healthcare systems and society. By 2030, it is projected that the number of individuals over the age of 65 will increase by nearly 1 billion, largely due to advancements in healthcare and improvements in quality of life. Aging is a multifaceted process that encompasses a wide array of changes, spanning from the cellular level to the intricate physiological systems of the human body. At the central nervous system level, aging represents a major risk factor for conditions such as depression and cognitive impairment, which are likely linked to neuroinflammatory processes and can potentially lead to more severe dementias, including Alzheimer’s disease (AD). The higher prevalence of AD in women compared to men has led to speculation that the onset of menopause and associated phenomena, particularly the decline in estrogen levels, may play a role in the development of the disease. Furthermore, research has shown that physical exercise confers both physical and mental health benefits to older adults, with women potentially experiencing the greatest advantages. Understanding the multifaceted nature of aging and its implications for health will ensure that older adults receive the support and care essential for maintaining their health and quality of life.
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spelling doaj.art-bae4c652f1414185b77a261be712af642024-03-27T14:00:31ZengMDPI AGPhysiologia2673-94882024-03-014111513810.3390/physiologia4010007Healthy Aging in Menopause: Prevention of Cognitive Decline, Depression and Dementia through Physical ExerciseCarmen Guerrero-González0Cristina Cueto-Ureña1Vanesa Cantón-Habas2María Jesús Ramírez-Expósito3José Manuel Martínez-Martos4Experimental and Clinical Physiopathology Research Group CTS-1039, Department of Health Sciences, School of Experimental and Health Sciences, University of Jaén, 23071 Jaén, SpainExperimental and Clinical Physiopathology Research Group CTS-1039, Department of Health Sciences, School of Experimental and Health Sciences, University of Jaén, 23071 Jaén, SpainDepartment of Nursing, Pharmacology and Physiotherapy, Faculty of Medicine and Nursing, University of Córdoba, Avda. Menéndez Pidal, s/n, 14004 Córdoba, SpainExperimental and Clinical Physiopathology Research Group CTS-1039, Department of Health Sciences, School of Experimental and Health Sciences, University of Jaén, 23071 Jaén, SpainExperimental and Clinical Physiopathology Research Group CTS-1039, Department of Health Sciences, School of Experimental and Health Sciences, University of Jaén, 23071 Jaén, SpainThe aging of the global population is a significant and complex phenomenon with far-reaching implications for healthcare systems and society. By 2030, it is projected that the number of individuals over the age of 65 will increase by nearly 1 billion, largely due to advancements in healthcare and improvements in quality of life. Aging is a multifaceted process that encompasses a wide array of changes, spanning from the cellular level to the intricate physiological systems of the human body. At the central nervous system level, aging represents a major risk factor for conditions such as depression and cognitive impairment, which are likely linked to neuroinflammatory processes and can potentially lead to more severe dementias, including Alzheimer’s disease (AD). The higher prevalence of AD in women compared to men has led to speculation that the onset of menopause and associated phenomena, particularly the decline in estrogen levels, may play a role in the development of the disease. Furthermore, research has shown that physical exercise confers both physical and mental health benefits to older adults, with women potentially experiencing the greatest advantages. Understanding the multifaceted nature of aging and its implications for health will ensure that older adults receive the support and care essential for maintaining their health and quality of life.https://www.mdpi.com/2673-9488/4/1/7agingcognitive impairmentdepressionAlzheimer’s diseasemenopauseneuroinflammation
spellingShingle Carmen Guerrero-González
Cristina Cueto-Ureña
Vanesa Cantón-Habas
María Jesús Ramírez-Expósito
José Manuel Martínez-Martos
Healthy Aging in Menopause: Prevention of Cognitive Decline, Depression and Dementia through Physical Exercise
Physiologia
aging
cognitive impairment
depression
Alzheimer’s disease
menopause
neuroinflammation
title Healthy Aging in Menopause: Prevention of Cognitive Decline, Depression and Dementia through Physical Exercise
title_full Healthy Aging in Menopause: Prevention of Cognitive Decline, Depression and Dementia through Physical Exercise
title_fullStr Healthy Aging in Menopause: Prevention of Cognitive Decline, Depression and Dementia through Physical Exercise
title_full_unstemmed Healthy Aging in Menopause: Prevention of Cognitive Decline, Depression and Dementia through Physical Exercise
title_short Healthy Aging in Menopause: Prevention of Cognitive Decline, Depression and Dementia through Physical Exercise
title_sort healthy aging in menopause prevention of cognitive decline depression and dementia through physical exercise
topic aging
cognitive impairment
depression
Alzheimer’s disease
menopause
neuroinflammation
url https://www.mdpi.com/2673-9488/4/1/7
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