Diabetes melutus associated with pentamidine isethionate in diffuse cutaneous leishmaniasis
The authors report a case of a male patient from Bacabal, MA with diffuse cutaneous leishmaniasis (DCL), for at least nine years, with 168 lesions on his body. These were tumour-like nodules with some ulceratmi. He usedpentavalent antimonial (glucantime®) and an association of gamma interferon plus...
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Medicina Tropical (SBMT)
1995-12-01
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| Series: | Revista da Sociedade Brasileira de Medicina Tropical |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821995000400015&lng=en&tlng=en |
| _version_ | 1817978715578040320 |
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| author | Jackson Mauricio Lopes Costa Marta Solange C. Moraes Ana Cristina R. Saldanha Aldina Barral Marcelo N. Burattini |
| author_facet | Jackson Mauricio Lopes Costa Marta Solange C. Moraes Ana Cristina R. Saldanha Aldina Barral Marcelo N. Burattini |
| author_sort | Jackson Mauricio Lopes Costa |
| collection | DOAJ |
| description | The authors report a case of a male patient from Bacabal, MA with diffuse cutaneous leishmaniasis (DCL), for at least nine years, with 168 lesions on his body. These were tumour-like nodules with some ulceratmi. He usedpentavalent antimonial (glucantime®) and an association of gamma interferon plus glucantime with improvement of the lesions but relapsed later. Recently, pentamidine isethionate (pentacarinat®) was given a dosage of 4mg/kg/weight/day on alternate days for 20 applications. After 3 months a similar course of 10 application was given 2 times. Later he developed diabetic signs with weight loss of 10kg, polydypsia, polyuria and xerostomia. The lower limbs lesions showed signs of activity. Blood glucose levels normalised and remain like this at moment. Attention is drawn to the fact that pentamidine isethionate should be used as a therapy option with care, obeyng rigorous laboratory controls including a glucose tolerance test. |
| first_indexed | 2024-04-13T22:33:46Z |
| format | Article |
| id | doaj.art-bae7d0e1ffaf4fe186b0a513b336a94a |
| institution | Directory Open Access Journal |
| issn | 1678-9849 |
| language | English |
| last_indexed | 2024-04-13T22:33:46Z |
| publishDate | 1995-12-01 |
| publisher | Sociedade Brasileira de Medicina Tropical (SBMT) |
| record_format | Article |
| series | Revista da Sociedade Brasileira de Medicina Tropical |
| spelling | doaj.art-bae7d0e1ffaf4fe186b0a513b336a94a2022-12-22T02:26:51ZengSociedade Brasileira de Medicina Tropical (SBMT)Revista da Sociedade Brasileira de Medicina Tropical1678-98491995-12-0128440540710.1590/S0037-86821995000400015S0037-86821995000400015Diabetes melutus associated with pentamidine isethionate in diffuse cutaneous leishmaniasisJackson Mauricio Lopes CostaMarta Solange C. MoraesAna Cristina R. SaldanhaAldina BarralMarcelo N. BurattiniThe authors report a case of a male patient from Bacabal, MA with diffuse cutaneous leishmaniasis (DCL), for at least nine years, with 168 lesions on his body. These were tumour-like nodules with some ulceratmi. He usedpentavalent antimonial (glucantime®) and an association of gamma interferon plus glucantime with improvement of the lesions but relapsed later. Recently, pentamidine isethionate (pentacarinat®) was given a dosage of 4mg/kg/weight/day on alternate days for 20 applications. After 3 months a similar course of 10 application was given 2 times. Later he developed diabetic signs with weight loss of 10kg, polydypsia, polyuria and xerostomia. The lower limbs lesions showed signs of activity. Blood glucose levels normalised and remain like this at moment. Attention is drawn to the fact that pentamidine isethionate should be used as a therapy option with care, obeyng rigorous laboratory controls including a glucose tolerance test.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821995000400015&lng=en&tlng=enLeishmaniose cutânea difusaIsotionato de pentamidinaDiabetes mellitusEstado do Maranhão |
| spellingShingle | Jackson Mauricio Lopes Costa Marta Solange C. Moraes Ana Cristina R. Saldanha Aldina Barral Marcelo N. Burattini Diabetes melutus associated with pentamidine isethionate in diffuse cutaneous leishmaniasis Revista da Sociedade Brasileira de Medicina Tropical Leishmaniose cutânea difusa Isotionato de pentamidina Diabetes mellitus Estado do Maranhão |
| title | Diabetes melutus associated with pentamidine isethionate in diffuse cutaneous leishmaniasis |
| title_full | Diabetes melutus associated with pentamidine isethionate in diffuse cutaneous leishmaniasis |
| title_fullStr | Diabetes melutus associated with pentamidine isethionate in diffuse cutaneous leishmaniasis |
| title_full_unstemmed | Diabetes melutus associated with pentamidine isethionate in diffuse cutaneous leishmaniasis |
| title_short | Diabetes melutus associated with pentamidine isethionate in diffuse cutaneous leishmaniasis |
| title_sort | diabetes melutus associated with pentamidine isethionate in diffuse cutaneous leishmaniasis |
| topic | Leishmaniose cutânea difusa Isotionato de pentamidina Diabetes mellitus Estado do Maranhão |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821995000400015&lng=en&tlng=en |
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