nLossFinder—A Graphical User Interface Program for the Nontargeted Detection of DNA Adducts

nLossFinder—A Graphical User Interface Program for the Nontargeted Detection of DNA Adducts

DNA adductomics is a relatively new omics approach aiming to measure known and unknown DNA modifications, called DNA adducts. Liquid chromatography–tandem mass spectrometry (LC-MS/MS) has become the most common method for analyzing DNA adducts. Recent advances in the field of mass spectrometry have...

Full description

Bibliographic Details
Main Authors:	Pedro F. M. Sousa, Giulia Martella, K. Magnus Åberg, Bahare Esfahani, Hitesh V. Motwani
Format:	Article
Language:	English
Published:	MDPI AG 2021-04-01
Series:	Toxics
Subjects:	DNA adducts high-resolution mass spectrometry data-independent acquisition MATLAB environmental monitoring
Online Access:	https://www.mdpi.com/2305-6304/9/4/78

Similar Items

AdductHunter: identifying protein-metal complex adducts in mass spectra
by: Derek Long, et al.
Published: (2024-02-01)

Detection of Benzo[<em>a</em>]pyrene Diol Epoxide Adducts to Histidine and Lysine in Serum Albumin In Vivo by High-Resolution-Tandem Mass Spectrometry
by: Javier Zurita, et al.
Published: (2022-01-01)

Current and Future Methodology for Quantitation and Site-Specific Mapping the Location of DNA Adducts
by: Gunnar Boysen, et al.
Published: (2022-01-01)

Characterization and quantitation of busulfan DNA adducts in the blood of patients receiving busulfan therapy
by: Valeria Guidolin, et al.
Published: (2023-03-01)

Keto-Enol Tautomerism in Passerini and Ugi Adducts
by: Pablo Pertejo, et al.
Published: (2021-02-01)

NEW ORGANOTIN (IV) OXALATO ADDUCTS: SYNTHESIS AND SPECTROSCOPIC STUDIES
by: SEYDI MANSOUR SY SECK, et al.
Published: (2012-06-01)

ROLE OF SCAPHOID IN THE ABDUCTION AND ADDUCTION MOVEMENTS OF WRIST JOINT
by: Sadik I Shaikh, et al.
Published: (2013-09-01)

Factors Influencing the Formation of Chemical–Hemoglobin Adducts
by: Yuko Shimamura, et al.
Published: (2021-12-01)

Inhibition of Giardia duodenalis by isocryptolepine -triazole adducts and derivatives
by: Supaluk Popruk, et al.
Published: (2024-12-01)

Correlation Investigation between Pyrrole-DNA and Pyrrole-Protein Adducts in Male ICR Mice Exposed to Retrorsine, a Hepatotoxic Pyrrolizidine Alkaloid
by: Lin Zhu, et al.
Published: (2022-05-01)

PHENYLPHOSPHONATO DERIVATIVES AND ADDUCT: SYNTHESIS AND SPECTROSCOPIC STUDIES
by: Bernard Mahieu, et al.
Published: (2010-07-01)

Metabolomics Analysis of Rabbit Plasma after Ocular Exposure to Vapors of Sulfur Mustard
by: Jihéne Bouhlel, et al.
Published: (2024-06-01)

Arytenoid adduction asymmetry among patients with laryngeal disorders
by: Babatunde Akinola Bamigboye, et al.
Published: (2024-03-01)

Protein adducts with lipid peroxidation products in patients with psoriasis
by: Adam Wroński, et al.
Published: (2023-07-01)

Estimation of intake and quantification of hemoglobin adducts of acrylamide in adolescents in Sweden
by: Efstathios Vryonidis, et al.
Published: (2024-06-01)

Protein Adducts and Protein Oxidation as Molecular Mechanisms of Flavonoid Bioactivity
by: P. Matthew Joyner
Published: (2021-08-01)

Synthesis, Crystallography, and Anti-Leukemic Activity of the Amino Adducts of Dehydroleucodine
by: Paola E. Ordóñez, et al.
Published: (2020-10-01)

Ochratoxin A: In Utero Exposure in Mice Induces Adducts in Testicular DNA
by: Jamie E. Jennings-Gee, et al.
Published: (2010-06-01)

The 4-Hydroxynonenal–Protein Adducts and Their Biological Relevance: Are Some Proteins Preferred Targets?
by: Lidija Milkovic, et al.
Published: (2023-04-01)

Formation and Identification of Six Amino Acid - Acrylamide Adducts and Their Cytotoxicity Toward Gastrointestinal Cell Lines
by: Dan Li, et al.
Published: (2022-05-01)

Two-fold addition reaction of silylene to C60: structural and electronic properties of a bis-adduct
by: Masahiro Kako, et al.
Published: (2024-05-01)

One-Step Synthesis, Crystallography, and Acute Toxicity of Two Boron–Carbohydrate Adducts That Induce Sedation in Mice
by: Ricardo Ivan Cordova-Chávez, et al.
Published: (2024-06-01)

Liquid Chromatographic Quadrupole Time-of-Flight Mass Spectrometric Untargeted Profiling of (Poly)phenolic Compounds in <i>Rubus idaeus</i> L. and <i>Rubus occidentalis</i> L. Fruits and Their Comparative Evaluation
by: Lapo Renai, et al.
Published: (2021-04-01)

Nontargeted identification of per- and polyfluoroalkyl substances in human follicular fluid and their blood-follicle transfer
by: Qiyue Kang, et al.
Published: (2020-06-01)

Formation of Cysteine Adducts with Chlorogenic Acid in Coffee Beans
by: Sorel Tchewonpi Sagu, et al.
Published: (2024-05-01)

Acrolein adducts and responding autoantibodies correlate with metabolic disturbance in Alzheimer’s disease
by: Monika Renuka Sanotra, et al.
Published: (2023-06-01)

Structure and Conformation of Novel BODIPY Ugi Adducts
by: Dr. Ismael Javier Arroyo‐Córdoba, et al.
Published: (2022-10-01)

The effect of the Copenhagen Adduction and Nordic Hamstring exercises on muscle strength and athletic performance: A quasi-experimental study
by: Christos Pippas, et al.
Published: (2025-03-01)

Fast Fourier Transform IR Characterization of Epoxy GY Systems Crosslinked with Aliphatic and Cycloaliphatic EH Polyamine Adducts
by: Caslav Lacnjevac, et al.
Published: (2010-01-01)

Molybdenum(V), germanium(IV), aluminum(III) and nickel(II) adducts with ethyleneurea, ethylenethiourea and propyleneurea: some empirical correlations involving TG and IR data
by: ROBSON F. DE FARIAS, et al.
Published: (2006-03-01)

NEW R2NH2OH (R = Cy, Bu) ADDUCTS OF MX2, MX3 OR MX5: SYNTHESIS AND INFRARED STUDY
by: NDONGO GUEYE, et al.
Published: (2013-12-01)

Identification of New Markers of Alcohol-Derived DNA Damage in Humans
by: Valeria Guidolin, et al.
Published: (2021-02-01)

Michael Adduct of Sulfonamide Chalcone Targets Folate Metabolism in Brugia Malayi Parasite
by: Priyanka S. Bhoj, et al.
Published: (2023-02-01)

Boosting cisplatin chemotherapy by nanomotor-enhanced tumor penetration and DNA adducts formation
by: Lihua Xu, et al.
Published: (2022-09-01)

Symmetry and gender differences of the knee joint adduction moment
by: Alexey B. Malkov, et al.
Published: (2020-10-01)

Synthesis, Biosynthesis, and Biological Activity of Diels–Alder Adducts from <i>Morus</i> Genus: An Update
by: Carola Tortora, et al.
Published: (2022-11-01)

Evaluation of DNA adduct damage using G-quadruplex-based DNAzyme
by: Yi Xiao, et al.
Published: (2023-05-01)

Human Brain Lipidomics: Utilities of Chloride Adducts in Flow Injection Analysis
by: Paul L. Wood, et al.
Published: (2021-04-01)

Mulberry Diels–Alder-type adducts: isolation, structure, bioactivity, and synthesis
by: Si-Yuan Luo, et al.
Published: (2022-09-01)

Copenhagen Adduction Exercise to Increase Eccentric Strength: A Systematic Review and Meta-Analysis
by: Jorge Pérez-Gómez, et al.
Published: (2020-04-01)