Frequency and risk factors for failed weaning from supplemental oxygen therapy after general anesthesia at a postanesthesia care unit: a retrospective cohort study
Abstract Background Patients are administered supplemental oxygen upon emergence from general anesthesia against the risk of hypoxia. However, few studies have assessed the weaning from supplemental oxygen therapy. This study investigated the frequency and risk factors of failure to discontinue supp...
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| Format: | Article |
| Language: | English |
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BMC
2023-07-01
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| Series: | BMC Anesthesiology |
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| Online Access: | https://doi.org/10.1186/s12871-023-02192-z |
| _version_ | 1797784445895311360 |
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| author | Yu Jeong Bang I Hyun Park Heejoon Jeong |
| author_facet | Yu Jeong Bang I Hyun Park Heejoon Jeong |
| author_sort | Yu Jeong Bang |
| collection | DOAJ |
| description | Abstract Background Patients are administered supplemental oxygen upon emergence from general anesthesia against the risk of hypoxia. However, few studies have assessed the weaning from supplemental oxygen therapy. This study investigated the frequency and risk factors of failure to discontinue supplemental oxygen at a postanesthesia care unit (PACU). Methods This retrospective cohort study was conducted in a tertiary hospital. We reviewed the medical records of adult patients admitted to the PACU after general anesthesia for elective surgery between January 2022 and November 2022. The primary endpoint was the frequency of failed weaning from supplemental oxygen therapy at PACU. A failed weaning was defined as oxygen saturation (SpO2) < 92% after discontinuing oxygen administration. The rate of failed discontinuation of supplemental oxygen at the PACU was assessed. Demographics, intraoperative, and postoperative factors were explored to determine potential associations with failed weaning from supplemental oxygen therapy using logistic regression analysis. Results We analyzed 12,109 patients. We identified 842 cases of failed weaning from supplemental oxygen therapy, with a frequency of 1:14 (95% confidence interval [CI], 1:15–1:13). Risk factors that showed the strongest associations with failed weaning included postoperative hypothermia (odds ratio [OR], 5.42; 95% CI, 4.40–6.68; P < 0.001), major abdominal surgery (OR, 4.04; 95% CI, 3.29–4.99; P < 0.001), and preoperative SpO2 < 92% in room air (OR, 3.15; 95% CI, 2.09–4.64; P < 0.001). Conclusion In the analysis of more than 12,000 general anesthetics, an overall risk of failed weaning from supplemental oxygen therapy of 1:14 was observed. The identified risk factors may help determine the discontinuation of supplemental oxygen administration at PACU. Trial registration Not applicable. |
| first_indexed | 2024-03-13T00:40:56Z |
| format | Article |
| id | doaj.art-baefd05d1e8b4cf79a52fa59d75772b2 |
| institution | Directory Open Access Journal |
| issn | 1471-2253 |
| language | English |
| last_indexed | 2024-03-13T00:40:56Z |
| publishDate | 2023-07-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Anesthesiology |
| spelling | doaj.art-baefd05d1e8b4cf79a52fa59d75772b22023-07-09T11:22:51ZengBMCBMC Anesthesiology1471-22532023-07-012311810.1186/s12871-023-02192-zFrequency and risk factors for failed weaning from supplemental oxygen therapy after general anesthesia at a postanesthesia care unit: a retrospective cohort studyYu Jeong Bang0I Hyun Park1Heejoon Jeong2Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of MedicineDepartment of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of MedicineDepartment of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of MedicineAbstract Background Patients are administered supplemental oxygen upon emergence from general anesthesia against the risk of hypoxia. However, few studies have assessed the weaning from supplemental oxygen therapy. This study investigated the frequency and risk factors of failure to discontinue supplemental oxygen at a postanesthesia care unit (PACU). Methods This retrospective cohort study was conducted in a tertiary hospital. We reviewed the medical records of adult patients admitted to the PACU after general anesthesia for elective surgery between January 2022 and November 2022. The primary endpoint was the frequency of failed weaning from supplemental oxygen therapy at PACU. A failed weaning was defined as oxygen saturation (SpO2) < 92% after discontinuing oxygen administration. The rate of failed discontinuation of supplemental oxygen at the PACU was assessed. Demographics, intraoperative, and postoperative factors were explored to determine potential associations with failed weaning from supplemental oxygen therapy using logistic regression analysis. Results We analyzed 12,109 patients. We identified 842 cases of failed weaning from supplemental oxygen therapy, with a frequency of 1:14 (95% confidence interval [CI], 1:15–1:13). Risk factors that showed the strongest associations with failed weaning included postoperative hypothermia (odds ratio [OR], 5.42; 95% CI, 4.40–6.68; P < 0.001), major abdominal surgery (OR, 4.04; 95% CI, 3.29–4.99; P < 0.001), and preoperative SpO2 < 92% in room air (OR, 3.15; 95% CI, 2.09–4.64; P < 0.001). Conclusion In the analysis of more than 12,000 general anesthetics, an overall risk of failed weaning from supplemental oxygen therapy of 1:14 was observed. The identified risk factors may help determine the discontinuation of supplemental oxygen administration at PACU. Trial registration Not applicable.https://doi.org/10.1186/s12871-023-02192-zSupplemental oxygenWeaningRisk factorPostanesthesia care unit |
| spellingShingle | Yu Jeong Bang I Hyun Park Heejoon Jeong Frequency and risk factors for failed weaning from supplemental oxygen therapy after general anesthesia at a postanesthesia care unit: a retrospective cohort study BMC Anesthesiology Supplemental oxygen Weaning Risk factor Postanesthesia care unit |
| title | Frequency and risk factors for failed weaning from supplemental oxygen therapy after general anesthesia at a postanesthesia care unit: a retrospective cohort study |
| title_full | Frequency and risk factors for failed weaning from supplemental oxygen therapy after general anesthesia at a postanesthesia care unit: a retrospective cohort study |
| title_fullStr | Frequency and risk factors for failed weaning from supplemental oxygen therapy after general anesthesia at a postanesthesia care unit: a retrospective cohort study |
| title_full_unstemmed | Frequency and risk factors for failed weaning from supplemental oxygen therapy after general anesthesia at a postanesthesia care unit: a retrospective cohort study |
| title_short | Frequency and risk factors for failed weaning from supplemental oxygen therapy after general anesthesia at a postanesthesia care unit: a retrospective cohort study |
| title_sort | frequency and risk factors for failed weaning from supplemental oxygen therapy after general anesthesia at a postanesthesia care unit a retrospective cohort study |
| topic | Supplemental oxygen Weaning Risk factor Postanesthesia care unit |
| url | https://doi.org/10.1186/s12871-023-02192-z |
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