Serum 25-hydroxyvitamin D concentration in Children with Lower Respiratory Tract Infection
Background: Vitamin D plays a critical role in the human body. Its deficiency had been proposed to play a role in lower respiratory tract infections [LRTIs], which responsible for 18% of deaths in young children. Aim of the work: The purpose of this study was to assess vitamin D concentrations in ch...
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| Format: | Article |
| Language: | English |
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Al-Azhar University, Faculty of Medicine (Damietta)
2020-10-01
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| Series: | International Journal of Medical Arts |
| Subjects: | |
| Online Access: | https://ijma.journals.ekb.eg/article_105776_c9bc007cc2cb113c32dc816ba06998b7.pdf |
| _version_ | 1818858561727365120 |
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| author | Asmaa Salah Barania Elbakry Mohammed Tharwat Elbakry Hany Abdel-Hady El-khaleegy Sabah Abdel-Raheem |
| author_facet | Asmaa Salah Barania Elbakry Mohammed Tharwat Elbakry Hany Abdel-Hady El-khaleegy Sabah Abdel-Raheem |
| author_sort | Asmaa Salah Barania |
| collection | DOAJ |
| description | Background: Vitamin D plays a critical role in the human body. Its deficiency had been proposed to play a role in lower respiratory tract infections [LRTIs], which responsible for 18% of deaths in young children. Aim of the work: The purpose of this study was to assess vitamin D concentrations in children with lower respiratory tract infections. Patients and Methods:After obtaining approval of the ethics committee, a prospective case control study was conducted in pediatric department, Damietta Faculty of Medicine, Al-Azhar University Hospital on children with lower respiratory tract infections and comparing 25-hydroxyvitamin D level between them and normal matched control from December 2018 to September 2019 include 140 children, Group A: 70 cases children had lower respiratory tract infections [LRTIs] either isolated pneumonia or associated with sepsis. Group B: matched with 70 healthy subjects. Results: There was significant reduction of vitamin D among study group children when compared to control group [13.68±5.50 s 40.64±4.76 ng/dl respectively]. There was no significant association between type of infection and vitamin D levels. However, all children with bronchitis had sufficient vitamin D levels. There were vitamin D-deficiency in 64.3% while No one was deficient vitamin D among control group. Conclusion: Children with acute lower respiratory tract infection had significant reduction in vitamin D levels. The reduction had no significant association with the type of infection. |
| first_indexed | 2024-12-19T08:58:15Z |
| format | Article |
| id | doaj.art-baf205e9cbd6497fb9ba9c9290e81771 |
| institution | Directory Open Access Journal |
| issn | 2636-4174 2682-3780 |
| language | English |
| last_indexed | 2024-12-19T08:58:15Z |
| publishDate | 2020-10-01 |
| publisher | Al-Azhar University, Faculty of Medicine (Damietta) |
| record_format | Article |
| series | International Journal of Medical Arts |
| spelling | doaj.art-baf205e9cbd6497fb9ba9c9290e817712022-12-21T20:28:34ZengAl-Azhar University, Faculty of Medicine (Damietta)International Journal of Medical Arts2636-41742682-37802020-10-012475776210.21608/ijma.2020.21996.1074105776Serum 25-hydroxyvitamin D concentration in Children with Lower Respiratory Tract InfectionAsmaa Salah Barania0Elbakry Mohammed Tharwat Elbakry1Hany Abdel-Hady El-khaleegy2Sabah Abdel-Raheem3Department of Pediatrics, Damanhour Teaching Hospital, Ministry of Health, EgyptDepartment of Pediatrics, Damietta Faculty of Medicine Al-Azhar University, EgyptDepartment of Pediatrics, Damietta Faculty of Medicine Al-Azhar University, EgyptDepartment of Clinical Pathology, Damietta Faculty of Medicine Al-Azhar University, EgyptBackground: Vitamin D plays a critical role in the human body. Its deficiency had been proposed to play a role in lower respiratory tract infections [LRTIs], which responsible for 18% of deaths in young children. Aim of the work: The purpose of this study was to assess vitamin D concentrations in children with lower respiratory tract infections. Patients and Methods:After obtaining approval of the ethics committee, a prospective case control study was conducted in pediatric department, Damietta Faculty of Medicine, Al-Azhar University Hospital on children with lower respiratory tract infections and comparing 25-hydroxyvitamin D level between them and normal matched control from December 2018 to September 2019 include 140 children, Group A: 70 cases children had lower respiratory tract infections [LRTIs] either isolated pneumonia or associated with sepsis. Group B: matched with 70 healthy subjects. Results: There was significant reduction of vitamin D among study group children when compared to control group [13.68±5.50 s 40.64±4.76 ng/dl respectively]. There was no significant association between type of infection and vitamin D levels. However, all children with bronchitis had sufficient vitamin D levels. There were vitamin D-deficiency in 64.3% while No one was deficient vitamin D among control group. Conclusion: Children with acute lower respiratory tract infection had significant reduction in vitamin D levels. The reduction had no significant association with the type of infection.https://ijma.journals.ekb.eg/article_105776_c9bc007cc2cb113c32dc816ba06998b7.pdf25-hydroxyvitamin dlower respiratory tract infectionpneumoniabronchiolitisbronchitis |
| spellingShingle | Asmaa Salah Barania Elbakry Mohammed Tharwat Elbakry Hany Abdel-Hady El-khaleegy Sabah Abdel-Raheem Serum 25-hydroxyvitamin D concentration in Children with Lower Respiratory Tract Infection International Journal of Medical Arts 25-hydroxyvitamin d lower respiratory tract infection pneumonia bronchiolitis bronchitis |
| title | Serum 25-hydroxyvitamin D concentration in Children with Lower Respiratory Tract Infection |
| title_full | Serum 25-hydroxyvitamin D concentration in Children with Lower Respiratory Tract Infection |
| title_fullStr | Serum 25-hydroxyvitamin D concentration in Children with Lower Respiratory Tract Infection |
| title_full_unstemmed | Serum 25-hydroxyvitamin D concentration in Children with Lower Respiratory Tract Infection |
| title_short | Serum 25-hydroxyvitamin D concentration in Children with Lower Respiratory Tract Infection |
| title_sort | serum 25 hydroxyvitamin d concentration in children with lower respiratory tract infection |
| topic | 25-hydroxyvitamin d lower respiratory tract infection pneumonia bronchiolitis bronchitis |
| url | https://ijma.journals.ekb.eg/article_105776_c9bc007cc2cb113c32dc816ba06998b7.pdf |
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