Resting Sinus Heart Rate and First Degree AV block: Modifiable Risk Predictors or Epiphenomena?

Simple and cost-effective tools that identify patients at increased risk for adverse cardiovascular events are actively sought. High resting sinus heart rate and first degree AV block are easily recognized and commonly encountered findings in a cardiology practice. A growing body of epidemiological...

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Main Authors: Rakesh Gopinathannair, Brian Olshansky
Format: Article
Language:English
Published: Elsevier 2009-11-01
Series:Indian Pacing and Electrophysiology Journal
Subjects:
Online Access:http://www.ipej.org/0906/rakesh.htm
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author Rakesh Gopinathannair
Brian Olshansky
author_facet Rakesh Gopinathannair
Brian Olshansky
author_sort Rakesh Gopinathannair
collection DOAJ
description Simple and cost-effective tools that identify patients at increased risk for adverse cardiovascular events are actively sought. High resting sinus heart rate and first degree AV block are easily recognized and commonly encountered findings in a cardiology practice. A growing body of epidemiological and clinical evidence has been shown them to be independent predictors of all-cause and cardiovascular mortality, both in the general population and in patients with structural heart disease. This paper reviews the important role of heart rate and first degree AV block in predicting cardiovascular outcomes, examines the pathophysiological mechanisms underlying this increased risk, and discusses the effectiveness of available therapies to favorably modify these risk factors.
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spelling doaj.art-baf2f7c1bcd847ecaff3247c490323702022-12-21T18:52:58ZengElsevierIndian Pacing and Electrophysiology Journal0972-62922009-11-0196334341Resting Sinus Heart Rate and First Degree AV block: Modifiable Risk Predictors or Epiphenomena?Rakesh GopinathannairBrian OlshanskySimple and cost-effective tools that identify patients at increased risk for adverse cardiovascular events are actively sought. High resting sinus heart rate and first degree AV block are easily recognized and commonly encountered findings in a cardiology practice. A growing body of epidemiological and clinical evidence has been shown them to be independent predictors of all-cause and cardiovascular mortality, both in the general population and in patients with structural heart disease. This paper reviews the important role of heart rate and first degree AV block in predicting cardiovascular outcomes, examines the pathophysiological mechanisms underlying this increased risk, and discusses the effectiveness of available therapies to favorably modify these risk factors.http://www.ipej.org/0906/rakesh.htmSinus heart ratefirst degree AV blockrisk predictorscardiovascular disease
spellingShingle Rakesh Gopinathannair
Brian Olshansky
Resting Sinus Heart Rate and First Degree AV block: Modifiable Risk Predictors or Epiphenomena?
Indian Pacing and Electrophysiology Journal
Sinus heart rate
first degree AV block
risk predictors
cardiovascular disease
title Resting Sinus Heart Rate and First Degree AV block: Modifiable Risk Predictors or Epiphenomena?
title_full Resting Sinus Heart Rate and First Degree AV block: Modifiable Risk Predictors or Epiphenomena?
title_fullStr Resting Sinus Heart Rate and First Degree AV block: Modifiable Risk Predictors or Epiphenomena?
title_full_unstemmed Resting Sinus Heart Rate and First Degree AV block: Modifiable Risk Predictors or Epiphenomena?
title_short Resting Sinus Heart Rate and First Degree AV block: Modifiable Risk Predictors or Epiphenomena?
title_sort resting sinus heart rate and first degree av block modifiable risk predictors or epiphenomena
topic Sinus heart rate
first degree AV block
risk predictors
cardiovascular disease
url http://www.ipej.org/0906/rakesh.htm
work_keys_str_mv AT rakeshgopinathannair restingsinusheartrateandfirstdegreeavblockmodifiableriskpredictorsorepiphenomena
AT brianolshansky restingsinusheartrateandfirstdegreeavblockmodifiableriskpredictorsorepiphenomena