Identification of Key Genes and Pathways in Genotoxic Stress Induced Endothelial Dysfunction: Results of Whole Transcriptome Sequencing

Identification of Key Genes and Pathways in Genotoxic Stress Induced Endothelial Dysfunction: Results of Whole Transcriptome Sequencing

Atherosclerosis is a leading cause of cardiovascular morbidity and mortality worldwide. Endothelial disfunction underlying the atherogenesis can be triggered by genotoxic stress in endothelial cells. In the presented research whole transcriptome sequencing (RNA-seq) of human coronary artery (HCAEC)...

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Bibliographic Details
Main Authors: Maxim Sinitsky, Anna Sinitskaya, Daria Shishkova, Alexey Tupikin, Maxim Asanov, Maria Khutornaya, Marsel Kabilov, Anastasia Ponasenko
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Biomedicines
Subjects:
mutagenesis
atherogenesis
endothelial disfunction
genotoxic stress
DNA damage
RNA-seq
Online Access:https://www.mdpi.com/2227-9059/10/9/2067

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