Application of CRISPR/Cas9 in Alzheimer’s Disease

Application of CRISPR/Cas9 in Alzheimer’s Disease

Alzheimer’s disease (AD) is a progressive and irreversible neurodegenerative disorder clinically characterized by cognitive impairment, abnormal behavior, and social deficits, which is intimately linked with excessive β-amyloid (Aβ) protein deposition along with many other misfolded proteins, neurof...

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Bibliographic Details
Main Authors: Likui Lu, Xi Yu, Yongle Cai, Miao Sun, Hao Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Neuroscience
Subjects:
gene therapy
CRISPR/Cas9
cognitive function
Alzheimer’s disease
delivery system
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2021.803894/full

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