Lung cancer and kidney injury: an updated review

Lung cancer is the leading cause of cancer deaths worldwide, accounting for an estimated 1.8 million deaths. Lung cancer is also the most common primary cancer leading to soft tissue (ST) metastasis. Renal disease may occur as a direct or indirect consequence of the cancer itself (e.g., postrenal ob...

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Main Authors: Bhargav Patel, Mohammad Ebrahimi Kalan, Maryam Khosravian, Audrey Tolouian, Ramin Tolouian, Mahnaz Aboufazeli, Masoumeh Asgharpour, Amirhesam Alirezaei
Format: Article
Language:English
Published: Society of Diabetic Nephropathy Prevention 2021-04-01
Series:Journal of Nephropathology
Subjects:
Online Access:https://nephropathol.com/PDF/jnp-10-e12.pdf
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author Bhargav Patel
Mohammad Ebrahimi Kalan
Maryam Khosravian
Audrey Tolouian
Ramin Tolouian
Mahnaz Aboufazeli
Masoumeh Asgharpour
Amirhesam Alirezaei
author_facet Bhargav Patel
Mohammad Ebrahimi Kalan
Maryam Khosravian
Audrey Tolouian
Ramin Tolouian
Mahnaz Aboufazeli
Masoumeh Asgharpour
Amirhesam Alirezaei
author_sort Bhargav Patel
collection DOAJ
description Lung cancer is the leading cause of cancer deaths worldwide, accounting for an estimated 1.8 million deaths. Lung cancer is also the most common primary cancer leading to soft tissue (ST) metastasis. Renal disease may occur as a direct or indirect consequence of the cancer itself (e.g., postrenal obstruction, compression, or infiltration), its treatment (e.g., radiotherapy or chemotherapy), or its related complications (e.g., opportunistic infection). Existing evidence shows that the most frequent primary solid tumor responsible for renal metastasis is pulmonary carcinoma, followed by gastric, breast, soft tissue, and thyroid carcinomas. Chronic kidney disease is a potential risk factor in the survival of patients with lung cancer. In this review, we will discuss causes of kidney injury in relation to lung cancer, potential mechanisms of kidney injury, and treatment options.
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spelling doaj.art-bafdb4fa037744a38971fc79f832b75c2023-05-13T11:25:48ZengSociety of Diabetic Nephropathy PreventionJournal of Nephropathology2251-83632251-88192021-04-01102e12e1210.34172/jnp.2021.12jnp-17114Lung cancer and kidney injury: an updated reviewBhargav Patel0Mohammad Ebrahimi Kalan1Maryam Khosravian2Audrey Tolouian3Ramin Tolouian4Mahnaz Aboufazeli5Masoumeh Asgharpour6Amirhesam Alirezaei7Department of Internal Medicine, University of Arizona, Tucson, AZ, USADepartment of Epidemiology, Robert Stempel College of Public Health, Florida International University, Miami, FL, USAInstitute of Biology, Martin Luther University Halle-Wittenberg, Halle (Saale), GermanyThe University of Texas at El Paso School of Nursing, El Paso, Texas, USADivision of Nephrology, Southern Arizona VA Healthcare System, Tucson, AZ, USADepartemt of Physical Therapy Education, Western University of Health Sciences, Pomona, California, USADepartment of Nephrology, Rouhani Hospital, Babol University of Medical Sciences, Babol, IranDepartment of Nephrology, Shahid Modarres Hospital, Shahid Beheshti University of Medical Sciences, Tehran, IranLung cancer is the leading cause of cancer deaths worldwide, accounting for an estimated 1.8 million deaths. Lung cancer is also the most common primary cancer leading to soft tissue (ST) metastasis. Renal disease may occur as a direct or indirect consequence of the cancer itself (e.g., postrenal obstruction, compression, or infiltration), its treatment (e.g., radiotherapy or chemotherapy), or its related complications (e.g., opportunistic infection). Existing evidence shows that the most frequent primary solid tumor responsible for renal metastasis is pulmonary carcinoma, followed by gastric, breast, soft tissue, and thyroid carcinomas. Chronic kidney disease is a potential risk factor in the survival of patients with lung cancer. In this review, we will discuss causes of kidney injury in relation to lung cancer, potential mechanisms of kidney injury, and treatment options.https://nephropathol.com/PDF/jnp-10-e12.pdfcancerkidney injurylung canceracute kidney injurychronic kidney diseasemetastasisnephrotic syndrome
spellingShingle Bhargav Patel
Mohammad Ebrahimi Kalan
Maryam Khosravian
Audrey Tolouian
Ramin Tolouian
Mahnaz Aboufazeli
Masoumeh Asgharpour
Amirhesam Alirezaei
Lung cancer and kidney injury: an updated review
Journal of Nephropathology
cancer
kidney injury
lung cancer
acute kidney injury
chronic kidney disease
metastasis
nephrotic syndrome
title Lung cancer and kidney injury: an updated review
title_full Lung cancer and kidney injury: an updated review
title_fullStr Lung cancer and kidney injury: an updated review
title_full_unstemmed Lung cancer and kidney injury: an updated review
title_short Lung cancer and kidney injury: an updated review
title_sort lung cancer and kidney injury an updated review
topic cancer
kidney injury
lung cancer
acute kidney injury
chronic kidney disease
metastasis
nephrotic syndrome
url https://nephropathol.com/PDF/jnp-10-e12.pdf
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AT maryamkhosravian lungcancerandkidneyinjuryanupdatedreview
AT audreytolouian lungcancerandkidneyinjuryanupdatedreview
AT ramintolouian lungcancerandkidneyinjuryanupdatedreview
AT mahnazaboufazeli lungcancerandkidneyinjuryanupdatedreview
AT masoumehasgharpour lungcancerandkidneyinjuryanupdatedreview
AT amirhesamalirezaei lungcancerandkidneyinjuryanupdatedreview