Biological control of gypsy moth (Lymantria dispar): an RNAi-based approach and a case for DNA insecticides
The discovery of the post-transcriptional gene silencing (PTGS) mechanism, widely known as RNAi (RNA interference),has contributed towards the elucidation of the cellular machinery involved in the response against viral infections based on gene silencing, and in developmental regulation of...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
University of Belgrade, University of Novi Sad
2016-01-01
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| Series: | Archives of Biological Sciences |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/0354-4664/2016/0354-46641600041N.pdf |
| Summary: | The discovery of the post-transcriptional gene silencing (PTGS) mechanism,
widely known as RNAi (RNA interference),has contributed towards the
elucidation of the cellular machinery involved in the response against viral
infections based on gene silencing, and in developmental regulation of
translational suppression. The application of RNAi in insect pest management
(IPM),and gene functional analysis, has been of enormous importance.
Unfortunately, as RNAi has many times proven to be difficult to examine in
Lepidoptera, focus has shifted to other potential post-genomic options in
IPM. Special attention has afforded to novel DNA insecticides based on
preparations of short single-stranded fragments of baculovirus anti-apoptosis
genes, which represent a safe and relatively rapid alternative approach for
IPM. This paper focuses on the draw backs and advantages of DNA insecticides
used in gypsy moth control and based on RNAi. |
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| ISSN: | 0354-4664 1821-4339 |