Lithography-based methods to manufacture biomaterials at small scales
Along with the search for new therapeutic agents, advanced formulation and fabrication of drug carriers are required for better targeting, sensing, and responding to environmental stimuli as well as maximizing treatment efficiency. The emergence of intelligent therapeutics involves the use of functi...
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Format: | Article |
Language: | English |
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Elsevier
2017-03-01
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Series: | Journal of Science: Advanced Materials and Devices |
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Online Access: | http://www.sciencedirect.com/science/article/pii/S2468217916301927 |
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author | Khanh T.M. Tran Thanh D. Nguyen |
author_facet | Khanh T.M. Tran Thanh D. Nguyen |
author_sort | Khanh T.M. Tran |
collection | DOAJ |
description | Along with the search for new therapeutic agents, advanced formulation and fabrication of drug carriers are required for better targeting, sensing, and responding to environmental stimuli as well as maximizing treatment efficiency. The emergence of intelligent therapeutics involves the use of functional biomaterials to mimic biological system for prolonged circulation and to work harmoniously with the body. One of the main concerns lies in the feasibility of creating systems with well-defined architectures including size, shape, components, and functionality. This review provides an overview regarding current challenges and potential of manufacturing and fabrication of biomaterials at small scales for various biomedical applications. Accordingly, novel lithography-based fabrication approaches are introduced together with their remarkable applications. Besides being popular in microelectronics, lithography techniques have demonstrated a great potential use for drug delivery, tissue engineering, and diagnostic tools. |
first_indexed | 2024-12-10T12:35:35Z |
format | Article |
id | doaj.art-bb00bd91ea7948aea8b85a27806fbc46 |
institution | Directory Open Access Journal |
issn | 2468-2179 |
language | English |
last_indexed | 2024-12-10T12:35:35Z |
publishDate | 2017-03-01 |
publisher | Elsevier |
record_format | Article |
series | Journal of Science: Advanced Materials and Devices |
spelling | doaj.art-bb00bd91ea7948aea8b85a27806fbc462022-12-22T01:48:41ZengElsevierJournal of Science: Advanced Materials and Devices2468-21792017-03-012111410.1016/j.jsamd.2016.12.001Lithography-based methods to manufacture biomaterials at small scalesKhanh T.M. Tran0Thanh D. Nguyen1Department of Mechanical Engineering, University of Connecticut, United StatesDepartment of Mechanical Engineering, University of Connecticut, United StatesAlong with the search for new therapeutic agents, advanced formulation and fabrication of drug carriers are required for better targeting, sensing, and responding to environmental stimuli as well as maximizing treatment efficiency. The emergence of intelligent therapeutics involves the use of functional biomaterials to mimic biological system for prolonged circulation and to work harmoniously with the body. One of the main concerns lies in the feasibility of creating systems with well-defined architectures including size, shape, components, and functionality. This review provides an overview regarding current challenges and potential of manufacturing and fabrication of biomaterials at small scales for various biomedical applications. Accordingly, novel lithography-based fabrication approaches are introduced together with their remarkable applications. Besides being popular in microelectronics, lithography techniques have demonstrated a great potential use for drug delivery, tissue engineering, and diagnostic tools.http://www.sciencedirect.com/science/article/pii/S2468217916301927LithographyBiomaterialsIntelligent therapeuticsDrug deliveryTissue engineeringBiosensors |
spellingShingle | Khanh T.M. Tran Thanh D. Nguyen Lithography-based methods to manufacture biomaterials at small scales Journal of Science: Advanced Materials and Devices Lithography Biomaterials Intelligent therapeutics Drug delivery Tissue engineering Biosensors |
title | Lithography-based methods to manufacture biomaterials at small scales |
title_full | Lithography-based methods to manufacture biomaterials at small scales |
title_fullStr | Lithography-based methods to manufacture biomaterials at small scales |
title_full_unstemmed | Lithography-based methods to manufacture biomaterials at small scales |
title_short | Lithography-based methods to manufacture biomaterials at small scales |
title_sort | lithography based methods to manufacture biomaterials at small scales |
topic | Lithography Biomaterials Intelligent therapeutics Drug delivery Tissue engineering Biosensors |
url | http://www.sciencedirect.com/science/article/pii/S2468217916301927 |
work_keys_str_mv | AT khanhtmtran lithographybasedmethodstomanufacturebiomaterialsatsmallscales AT thanhdnguyen lithographybasedmethodstomanufacturebiomaterialsatsmallscales |