Lithography-based methods to manufacture biomaterials at small scales

Along with the search for new therapeutic agents, advanced formulation and fabrication of drug carriers are required for better targeting, sensing, and responding to environmental stimuli as well as maximizing treatment efficiency. The emergence of intelligent therapeutics involves the use of functi...

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Main Authors: Khanh T.M. Tran, Thanh D. Nguyen
Format: Article
Language:English
Published: Elsevier 2017-03-01
Series:Journal of Science: Advanced Materials and Devices
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2468217916301927
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author Khanh T.M. Tran
Thanh D. Nguyen
author_facet Khanh T.M. Tran
Thanh D. Nguyen
author_sort Khanh T.M. Tran
collection DOAJ
description Along with the search for new therapeutic agents, advanced formulation and fabrication of drug carriers are required for better targeting, sensing, and responding to environmental stimuli as well as maximizing treatment efficiency. The emergence of intelligent therapeutics involves the use of functional biomaterials to mimic biological system for prolonged circulation and to work harmoniously with the body. One of the main concerns lies in the feasibility of creating systems with well-defined architectures including size, shape, components, and functionality. This review provides an overview regarding current challenges and potential of manufacturing and fabrication of biomaterials at small scales for various biomedical applications. Accordingly, novel lithography-based fabrication approaches are introduced together with their remarkable applications. Besides being popular in microelectronics, lithography techniques have demonstrated a great potential use for drug delivery, tissue engineering, and diagnostic tools.
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spelling doaj.art-bb00bd91ea7948aea8b85a27806fbc462022-12-22T01:48:41ZengElsevierJournal of Science: Advanced Materials and Devices2468-21792017-03-012111410.1016/j.jsamd.2016.12.001Lithography-based methods to manufacture biomaterials at small scalesKhanh T.M. Tran0Thanh D. Nguyen1Department of Mechanical Engineering, University of Connecticut, United StatesDepartment of Mechanical Engineering, University of Connecticut, United StatesAlong with the search for new therapeutic agents, advanced formulation and fabrication of drug carriers are required for better targeting, sensing, and responding to environmental stimuli as well as maximizing treatment efficiency. The emergence of intelligent therapeutics involves the use of functional biomaterials to mimic biological system for prolonged circulation and to work harmoniously with the body. One of the main concerns lies in the feasibility of creating systems with well-defined architectures including size, shape, components, and functionality. This review provides an overview regarding current challenges and potential of manufacturing and fabrication of biomaterials at small scales for various biomedical applications. Accordingly, novel lithography-based fabrication approaches are introduced together with their remarkable applications. Besides being popular in microelectronics, lithography techniques have demonstrated a great potential use for drug delivery, tissue engineering, and diagnostic tools.http://www.sciencedirect.com/science/article/pii/S2468217916301927LithographyBiomaterialsIntelligent therapeuticsDrug deliveryTissue engineeringBiosensors
spellingShingle Khanh T.M. Tran
Thanh D. Nguyen
Lithography-based methods to manufacture biomaterials at small scales
Journal of Science: Advanced Materials and Devices
Lithography
Biomaterials
Intelligent therapeutics
Drug delivery
Tissue engineering
Biosensors
title Lithography-based methods to manufacture biomaterials at small scales
title_full Lithography-based methods to manufacture biomaterials at small scales
title_fullStr Lithography-based methods to manufacture biomaterials at small scales
title_full_unstemmed Lithography-based methods to manufacture biomaterials at small scales
title_short Lithography-based methods to manufacture biomaterials at small scales
title_sort lithography based methods to manufacture biomaterials at small scales
topic Lithography
Biomaterials
Intelligent therapeutics
Drug delivery
Tissue engineering
Biosensors
url http://www.sciencedirect.com/science/article/pii/S2468217916301927
work_keys_str_mv AT khanhtmtran lithographybasedmethodstomanufacturebiomaterialsatsmallscales
AT thanhdnguyen lithographybasedmethodstomanufacturebiomaterialsatsmallscales