Staging of amyloid β, t‐tau, regional atrophy rates, and cognitive change in a nondemented cohort: Results of serial mediation analyses
Abstract Introduction Current models posit a sequence of amyloid β (Aβ), tau, atrophy, and cognitive change leading to Alzheimer's disease, but ambiguities remain. We examined these sequences via serial mediations. Methods We studied normal controls, early mild cognitive impairment, and late mi...
Main Authors: | Evan Fletcher, Teresa Jenica Filshtein, Danielle Harvey, Alice Renaud, Dan Mungas, Charles DeCarli, Alzheimer's Disease Neuroimaging Initiative |
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Format: | Article |
Language: | English |
Published: |
Wiley
2018-01-01
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Series: | Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring |
Subjects: | |
Online Access: | https://doi.org/10.1016/j.dadm.2018.04.001 |
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