Comprehensive mutation profiling and mRNA expression analysis in atypical chronic myeloid leukemia in comparison with chronic myelomonocytic leukemia

Comprehensive mutation profiling and mRNA expression analysis in atypical chronic myeloid leukemia in comparison with chronic myelomonocytic leukemia

Abstract Atypical chronic myeloid leukemia (aCML) and chronic myelomonocytic leukemia (CMML) represent two histologically and clinically overlapping myelodysplastic/myeloproliferative neoplasms. Also the mutational landscapes of both entities show congruencies. We analyzed and compared an aCML cohor...

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Bibliographic Details
Main Authors: Muhammad Faisal, Helge Stark, Guntram Büsche, Jerome Schlue, Kristin Teiken, Hans H. Kreipe, Ulrich Lehmann, Stephan Bartels
Format: Article
Language:English
Published: Wiley 2019-02-01
Series:Cancer Medicine
Subjects:
aCML
CMML
machine learning algorithm
nCounter
NGS
Online Access:https://doi.org/10.1002/cam4.1946

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