Clinicoetiological profile of cerebral venous sinus thrombosis patients at a tertiary care center
Background: Cerebral venous sinus thrombosis (CVST) accounts for 10%–20% of strokes in young persons. In India, CVST accounts for around 30% of all strokes. The majority of CVSTs are caused by procoagulant circumstances, with pregnancy and early puerperium being well-established risk factors. The st...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2023-01-01
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| Series: | Current Medical Issues |
| Subjects: | |
| Online Access: | http://www.cmijournal.org/article.asp?issn=0973-4651;year=2023;volume=21;issue=1;spage=14;epage=18;aulast=Raina |
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| author | Adnan Firdous Raina Amit Chandra Waseem Dar Hilal Ahmad Ganie Zubair Kawaja Maqbool Wani Ravouf Asimi |
| author_facet | Adnan Firdous Raina Amit Chandra Waseem Dar Hilal Ahmad Ganie Zubair Kawaja Maqbool Wani Ravouf Asimi |
| author_sort | Adnan Firdous Raina |
| collection | DOAJ |
| description | Background: Cerebral venous sinus thrombosis (CVST) accounts for 10%–20% of strokes in young persons. In India, CVST accounts for around 30% of all strokes. The majority of CVSTs are caused by procoagulant circumstances, with pregnancy and early puerperium being well-established risk factors. The study aimed to look into the clinical profile, radiological characteristics, etiological variables, and outcome of CVST in venous stroke patients admitted to a tertiary care facility. Methods: We included individuals between the ages of 18 and 75 years who had a cerebral venous thrombosis (CVT) diagnosis confirmed by magnetic resonance imaging (MRI) + magnetic resonance venography computed tomography (CT) plus CT venography. The research included all individuals suspected of having CVST with or without particular neurological deficits and a confirmed imaging diagnosis. Patients were removed in situations of ambiguous neuroimaging, arterial strokes, space-occupying lesions, metabolic encephalopathy, and patient reluctance to participate. Results: This study included 82 patients, 21 (25.6%) males and 61 (74.4%) of whom were females. The most common presenting symptom was headache (79.2%), followed by vomiting (54.8%) and abnormal sensorium (35.3%). In this study, 34/82 (41.4%) patients had evident clinical triggers and were classified as induced CVT. Para infectious disease was recognized as a risk factor for CVT in 13/34 (38.2%) patients. A prothrombotic conditions could be established in 48 (58.5%) of these patients. Conclusion: CVST is a treatable and reversible cause of stroke in adolescents. The clinical presentation varies greatly, and symptoms may appear gradually over weeks or months. Although it is still an uncommon cause of headache and stroke, MRI has allowed for early detection. |
| first_indexed | 2024-04-10T09:56:55Z |
| format | Article |
| id | doaj.art-bb08e0f27f3b4169a358b7cea0fe2554 |
| institution | Directory Open Access Journal |
| issn | 0973-4651 2666-4054 |
| language | English |
| last_indexed | 2024-04-10T09:56:55Z |
| publishDate | 2023-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Current Medical Issues |
| spelling | doaj.art-bb08e0f27f3b4169a358b7cea0fe25542023-02-16T12:13:30ZengWolters Kluwer Medknow PublicationsCurrent Medical Issues0973-46512666-40542023-01-01211141810.4103/cmi.cmi_111_22Clinicoetiological profile of cerebral venous sinus thrombosis patients at a tertiary care centerAdnan Firdous RainaAmit ChandraWaseem DarHilal Ahmad GanieZubair KawajaMaqbool WaniRavouf AsimiBackground: Cerebral venous sinus thrombosis (CVST) accounts for 10%–20% of strokes in young persons. In India, CVST accounts for around 30% of all strokes. The majority of CVSTs are caused by procoagulant circumstances, with pregnancy and early puerperium being well-established risk factors. The study aimed to look into the clinical profile, radiological characteristics, etiological variables, and outcome of CVST in venous stroke patients admitted to a tertiary care facility. Methods: We included individuals between the ages of 18 and 75 years who had a cerebral venous thrombosis (CVT) diagnosis confirmed by magnetic resonance imaging (MRI) + magnetic resonance venography computed tomography (CT) plus CT venography. The research included all individuals suspected of having CVST with or without particular neurological deficits and a confirmed imaging diagnosis. Patients were removed in situations of ambiguous neuroimaging, arterial strokes, space-occupying lesions, metabolic encephalopathy, and patient reluctance to participate. Results: This study included 82 patients, 21 (25.6%) males and 61 (74.4%) of whom were females. The most common presenting symptom was headache (79.2%), followed by vomiting (54.8%) and abnormal sensorium (35.3%). In this study, 34/82 (41.4%) patients had evident clinical triggers and were classified as induced CVT. Para infectious disease was recognized as a risk factor for CVT in 13/34 (38.2%) patients. A prothrombotic conditions could be established in 48 (58.5%) of these patients. Conclusion: CVST is a treatable and reversible cause of stroke in adolescents. The clinical presentation varies greatly, and symptoms may appear gradually over weeks or months. Although it is still an uncommon cause of headache and stroke, MRI has allowed for early detection.http://www.cmijournal.org/article.asp?issn=0973-4651;year=2023;volume=21;issue=1;spage=14;epage=18;aulast=Rainacerebral venous thrombosishemorrhagic infarctheparinrisk factorsvenography |
| spellingShingle | Adnan Firdous Raina Amit Chandra Waseem Dar Hilal Ahmad Ganie Zubair Kawaja Maqbool Wani Ravouf Asimi Clinicoetiological profile of cerebral venous sinus thrombosis patients at a tertiary care center Current Medical Issues cerebral venous thrombosis hemorrhagic infarct heparin risk factors venography |
| title | Clinicoetiological profile of cerebral venous sinus thrombosis patients at a tertiary care center |
| title_full | Clinicoetiological profile of cerebral venous sinus thrombosis patients at a tertiary care center |
| title_fullStr | Clinicoetiological profile of cerebral venous sinus thrombosis patients at a tertiary care center |
| title_full_unstemmed | Clinicoetiological profile of cerebral venous sinus thrombosis patients at a tertiary care center |
| title_short | Clinicoetiological profile of cerebral venous sinus thrombosis patients at a tertiary care center |
| title_sort | clinicoetiological profile of cerebral venous sinus thrombosis patients at a tertiary care center |
| topic | cerebral venous thrombosis hemorrhagic infarct heparin risk factors venography |
| url | http://www.cmijournal.org/article.asp?issn=0973-4651;year=2023;volume=21;issue=1;spage=14;epage=18;aulast=Raina |
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