Fertility Preservation Strategies in Cancer Patients: A Comprehensive Review
Introduction and purpose. Preserving fertility is crucial for cancer patients, aligning with advancements in oncology. As survival rates improve, addressing treatment-related late effects gains importance. Many young patients, aware of therapy toxicity, consider future conception chances, impacting...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Kazimierz Wielki University
2024-02-01
|
| Series: | Journal of Education, Health and Sport |
| Subjects: | |
| Online Access: | https://apcz.umk.pl/JEHS/article/view/48362 |
| _version_ | 1827347662245986304 |
|---|---|
| author | Michał Razik Piotr Bator Patrycja Rozwadowska Jan Ramian Jakub Rybak Barbara Magiera Karol Magiera Wiktor Razik |
| author_facet | Michał Razik Piotr Bator Patrycja Rozwadowska Jan Ramian Jakub Rybak Barbara Magiera Karol Magiera Wiktor Razik |
| author_sort | Michał Razik |
| collection | DOAJ |
| description |
Introduction and purpose. Preserving fertility is crucial for cancer patients, aligning with advancements in oncology. As survival rates improve, addressing treatment-related late effects gains importance. Many young patients, aware of therapy toxicity, consider future conception chances, impacting treatment decisions. With a trend toward delayed childbirth and a growing population facing unplanned family planning disruptions, the demand for fertility preservation is expected to rise. This paper provides a brief review of available methods for preserving fertility in cancer patients.
State of knowledge. Freezing semen in liquid nitrogen vapor is a standard method for preserving reproductive potential in male cancer patients. Shielding during total-body radiation limits testicular volume reduction, indicating less damage to the germinal epithelium. Hormone suppression treatments are not protective in male cancer patients. Oocyte and embryo cryopreservation are considered secure methods before anticancer treatments, with oocyte cryopreservation being preferred for post-pubertal women. Ovarian tissue cryopreservation remains an alternative method without preliminary treatment, suitable when time is insufficient for ovarian stimulation. Ovarian transposition beyond the intended radiation area, performed laparoscopically, can retain ovarian function. GnRH agonist administration before and during chemotherapy aims to minimize the likelihood of premature ovarian insufficiency.
Summary. Advancements in fertility preservation for cancer patients, ranging from traditional cryopreservation to innovative methods like ovarian tissue preservation, highlight a commitment to empowering individuals facing cancer diagnoses. Ongoing research expands possibilities, ensuring a diverse range of strategies that offer tangible and hopeful prospects at the intersection of cancer and reproductive health.
|
| first_indexed | 2024-03-07T23:55:11Z |
| format | Article |
| id | doaj.art-bb08f1ce4ec94828862777994d43211f |
| institution | Directory Open Access Journal |
| issn | 2391-8306 |
| language | English |
| last_indexed | 2024-03-07T23:55:11Z |
| publishDate | 2024-02-01 |
| publisher | Kazimierz Wielki University |
| record_format | Article |
| series | Journal of Education, Health and Sport |
| spelling | doaj.art-bb08f1ce4ec94828862777994d43211f2024-02-18T11:52:53ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062024-02-016110.12775/JEHS.2024.61.008Fertility Preservation Strategies in Cancer Patients: A Comprehensive ReviewMichał Razik0Piotr Bator1Patrycja Rozwadowska2Jan Ramian3Jakub Rybak4Barbara Magiera5Karol Magiera6Wiktor Razik7Faculty of Medical Sciences in Katowice, Medical University of Silesia, Katowice, PolandFaculty of Medical Sciences in Katowice, Medical University of Silesia, Katowice, PolandFaculty of Medical Sciences in Katowice, Medical University of Silesia, Katowice, PolandFaculty of Medical Sciences in Katowice, Medical University of Silesia, Katowice, PolandFaculty of Medical Sciences in Katowice, Medical University of Silesia, Katowice, PolandProf. K. Gibiński University Clinical Center of the Medical University of Silesia in Katowice, Medyków 14, 40-752 Katowice, PolandFaculty of Medical Sciences in Katowice, Medical University of Silesia, Katowice, PolandFaculty of Medical Sciences in Katowice, Medical University of Silesia, Katowice, Poland Introduction and purpose. Preserving fertility is crucial for cancer patients, aligning with advancements in oncology. As survival rates improve, addressing treatment-related late effects gains importance. Many young patients, aware of therapy toxicity, consider future conception chances, impacting treatment decisions. With a trend toward delayed childbirth and a growing population facing unplanned family planning disruptions, the demand for fertility preservation is expected to rise. This paper provides a brief review of available methods for preserving fertility in cancer patients. State of knowledge. Freezing semen in liquid nitrogen vapor is a standard method for preserving reproductive potential in male cancer patients. Shielding during total-body radiation limits testicular volume reduction, indicating less damage to the germinal epithelium. Hormone suppression treatments are not protective in male cancer patients. Oocyte and embryo cryopreservation are considered secure methods before anticancer treatments, with oocyte cryopreservation being preferred for post-pubertal women. Ovarian tissue cryopreservation remains an alternative method without preliminary treatment, suitable when time is insufficient for ovarian stimulation. Ovarian transposition beyond the intended radiation area, performed laparoscopically, can retain ovarian function. GnRH agonist administration before and during chemotherapy aims to minimize the likelihood of premature ovarian insufficiency. Summary. Advancements in fertility preservation for cancer patients, ranging from traditional cryopreservation to innovative methods like ovarian tissue preservation, highlight a commitment to empowering individuals facing cancer diagnoses. Ongoing research expands possibilities, ensuring a diverse range of strategies that offer tangible and hopeful prospects at the intersection of cancer and reproductive health. https://apcz.umk.pl/JEHS/article/view/48362cancerfertilitypregnancy |
| spellingShingle | Michał Razik Piotr Bator Patrycja Rozwadowska Jan Ramian Jakub Rybak Barbara Magiera Karol Magiera Wiktor Razik Fertility Preservation Strategies in Cancer Patients: A Comprehensive Review Journal of Education, Health and Sport cancer fertility pregnancy |
| title | Fertility Preservation Strategies in Cancer Patients: A Comprehensive Review |
| title_full | Fertility Preservation Strategies in Cancer Patients: A Comprehensive Review |
| title_fullStr | Fertility Preservation Strategies in Cancer Patients: A Comprehensive Review |
| title_full_unstemmed | Fertility Preservation Strategies in Cancer Patients: A Comprehensive Review |
| title_short | Fertility Preservation Strategies in Cancer Patients: A Comprehensive Review |
| title_sort | fertility preservation strategies in cancer patients a comprehensive review |
| topic | cancer fertility pregnancy |
| url | https://apcz.umk.pl/JEHS/article/view/48362 |
| work_keys_str_mv | AT michałrazik fertilitypreservationstrategiesincancerpatientsacomprehensivereview AT piotrbator fertilitypreservationstrategiesincancerpatientsacomprehensivereview AT patrycjarozwadowska fertilitypreservationstrategiesincancerpatientsacomprehensivereview AT janramian fertilitypreservationstrategiesincancerpatientsacomprehensivereview AT jakubrybak fertilitypreservationstrategiesincancerpatientsacomprehensivereview AT barbaramagiera fertilitypreservationstrategiesincancerpatientsacomprehensivereview AT karolmagiera fertilitypreservationstrategiesincancerpatientsacomprehensivereview AT wiktorrazik fertilitypreservationstrategiesincancerpatientsacomprehensivereview |