Effect of preterm birth on early neonatal, late neonatal, and postneonatal mortality in India.
Despite India having a high burden of infant deaths and preterm birth, there is a clear lack of studies documenting association between preterm birth and infant mortality in India. Additionally, existing studies have failed to account for unobserved heterogeneity while linking preterm birth with inf...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2022-01-01
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| Series: | PLOS Global Public Health |
| Online Access: | https://doi.org/10.1371/journal.pgph.0000205 |
| _version_ | 1797697990220054528 |
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| author | Ajit Kumar Kannaujiya Kaushalendra Kumar Ashish Kumar Upadhyay Lotus McDougal Anita Raj K S James Abhishek Singh |
| author_facet | Ajit Kumar Kannaujiya Kaushalendra Kumar Ashish Kumar Upadhyay Lotus McDougal Anita Raj K S James Abhishek Singh |
| author_sort | Ajit Kumar Kannaujiya |
| collection | DOAJ |
| description | Despite India having a high burden of infant deaths and preterm birth, there is a clear lack of studies documenting association between preterm birth and infant mortality in India. Additionally, existing studies have failed to account for unobserved heterogeneity while linking preterm birth with infant mortality. Hence, the present study examines association of preterm birth with early neonatal death (ENND), late neonatal death (LNND), and postneonatal death (PNND) in India. We used the reproductive calendar canvassed in the cross-sectional National Family Health Survey 2015-16 (NFHS-4) to identify preterm births. We used multivariable logistic regression to examine the associations for all births, most-, second most-, and third most- recent births occurred in five years preceding NFHS-4. We use mother fixed-effect logistic regression to confirm the associations among all recent births. Among all births, preterm births were 4.2, 3.8, and 1.7 times as likely as full-term births to die during early neonatal, late neonatal, and postneonatal periods respectively. Among most recent births, preterm births were 4.4, 4.0, and 2.0 times as likely as full-term births to die during early neonatal, late neonatal, and postneonatal periods respectively. Preterm births were also associated with risk of only ENND, LNND, and PNND among the second most recent births. Preterm births were associated with risk of only ENND and LNND among the third most recent births. Preterm births were also associated with ENND, LNND, and PNND in the mother fixed-effects regressions. This study establishes associations of preterm birth with ENND, LNND, and PNND in India using over 0.2 million births that occurred in 5 years preceding one of the largest population-based representative household surveys conducted in any part of the world. Our findings call for programmatic and policy interventions to address the considerable burden of preterm birth in the country. |
| first_indexed | 2024-03-12T03:47:47Z |
| format | Article |
| id | doaj.art-bb1721fc13d84dff8d349b74b96fd258 |
| institution | Directory Open Access Journal |
| issn | 2767-3375 |
| language | English |
| last_indexed | 2024-03-12T03:47:47Z |
| publishDate | 2022-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLOS Global Public Health |
| spelling | doaj.art-bb1721fc13d84dff8d349b74b96fd2582023-09-03T12:41:14ZengPublic Library of Science (PLoS)PLOS Global Public Health2767-33752022-01-0126e000020510.1371/journal.pgph.0000205Effect of preterm birth on early neonatal, late neonatal, and postneonatal mortality in India.Ajit Kumar KannaujiyaKaushalendra KumarAshish Kumar UpadhyayLotus McDougalAnita RajK S JamesAbhishek SinghDespite India having a high burden of infant deaths and preterm birth, there is a clear lack of studies documenting association between preterm birth and infant mortality in India. Additionally, existing studies have failed to account for unobserved heterogeneity while linking preterm birth with infant mortality. Hence, the present study examines association of preterm birth with early neonatal death (ENND), late neonatal death (LNND), and postneonatal death (PNND) in India. We used the reproductive calendar canvassed in the cross-sectional National Family Health Survey 2015-16 (NFHS-4) to identify preterm births. We used multivariable logistic regression to examine the associations for all births, most-, second most-, and third most- recent births occurred in five years preceding NFHS-4. We use mother fixed-effect logistic regression to confirm the associations among all recent births. Among all births, preterm births were 4.2, 3.8, and 1.7 times as likely as full-term births to die during early neonatal, late neonatal, and postneonatal periods respectively. Among most recent births, preterm births were 4.4, 4.0, and 2.0 times as likely as full-term births to die during early neonatal, late neonatal, and postneonatal periods respectively. Preterm births were also associated with risk of only ENND, LNND, and PNND among the second most recent births. Preterm births were associated with risk of only ENND and LNND among the third most recent births. Preterm births were also associated with ENND, LNND, and PNND in the mother fixed-effects regressions. This study establishes associations of preterm birth with ENND, LNND, and PNND in India using over 0.2 million births that occurred in 5 years preceding one of the largest population-based representative household surveys conducted in any part of the world. Our findings call for programmatic and policy interventions to address the considerable burden of preterm birth in the country.https://doi.org/10.1371/journal.pgph.0000205 |
| spellingShingle | Ajit Kumar Kannaujiya Kaushalendra Kumar Ashish Kumar Upadhyay Lotus McDougal Anita Raj K S James Abhishek Singh Effect of preterm birth on early neonatal, late neonatal, and postneonatal mortality in India. PLOS Global Public Health |
| title | Effect of preterm birth on early neonatal, late neonatal, and postneonatal mortality in India. |
| title_full | Effect of preterm birth on early neonatal, late neonatal, and postneonatal mortality in India. |
| title_fullStr | Effect of preterm birth on early neonatal, late neonatal, and postneonatal mortality in India. |
| title_full_unstemmed | Effect of preterm birth on early neonatal, late neonatal, and postneonatal mortality in India. |
| title_short | Effect of preterm birth on early neonatal, late neonatal, and postneonatal mortality in India. |
| title_sort | effect of preterm birth on early neonatal late neonatal and postneonatal mortality in india |
| url | https://doi.org/10.1371/journal.pgph.0000205 |
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