On the Selective Packaging of Genomic RNA by HIV-1

On the Selective Packaging of Genomic RNA by HIV-1

Like other retroviruses, human immunodeficiency virus type 1 (HIV-1) selectively packages genomic RNA (gRNA) during virus assembly. However, in the absence of the gRNA, cellular messenger RNAs (mRNAs) are packaged. While the gRNA is selected because of its cis-acting packaging signal, the mechanism...

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Bibliographic Details
Main Authors: Mauricio Comas-Garcia, Sean R. Davis, Alan Rein
Format: Article
Language:English
Published: MDPI AG 2016-09-01
Series:Viruses
Subjects:
retroviruses
retroviral RNA
virus assembly
HIV-1
selective RNA packaging
genomic RNA
packaging
encapsidation
capsid
RNA-protein interactions
Online Access:http://www.mdpi.com/1999-4915/8/9/246

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