Role of General Anesthesia and Rapid On-site Evaluation in the Diagnosis of Lung Cancer with EBUS-TBNA
Background and objective Lung cancer is a common malignant tumor of respiratory system. Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a valuable tool for the diagnosis and staging of lung cancer. EBUS-TBNA is predominantly performed under local anesthesia or conscio...
| Main Authors: | , |
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| Format: | Article |
| Language: | zho |
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Chinese Anti-Cancer Association; Chinese Antituberculosis Association
2024-02-01
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| Series: | Chinese Journal of Lung Cancer |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.3779/j.issn.1009-3419.2024.102.07 |
| _version_ | 1797271204952801280 |
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| author | Yuhe HU Yuying LI |
| author_facet | Yuhe HU Yuying LI |
| author_sort | Yuhe HU |
| collection | DOAJ |
| description | Background and objective Lung cancer is a common malignant tumor of respiratory system. Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a valuable tool for the diagnosis and staging of lung cancer. EBUS-TBNA is predominantly performed under local anesthesia or conscious sedation. However, the diagnostic performance of EBUS-TBNA under general anesthesia and in conjunction with rapid on-site evaluation (ROSE) remains uncertain. This study aims to investigate the value of general anesthesia and ROSE in the diagnosis of lung cancer with EBUS-TBNA. Methods A retrospective analysis was conducted on 164 patients treated in the Department of Respiratory and Critical Care Medicine of The Affiliated Hospital of Southwest Medical University from January 2018 to December 2022. All patients were preoperatively suspected of lung cancer and underwent EBUS-TBNA. Based on whether they received general anesthesia and ROSE, the patients were divided into three groups: local anesthesia group (LA group)(n=54), general anesthesia group (GA group)(n=67) and general anesthesia with ROSE group (GA-ROSE group)(n=43). The puncture characteristics and diagnostic differences were analyzed among the groups. Results The number of lymph node puncture needles in the LA group was higher than in GA-ROSE group (P<0.01). The overall diagnostic rates of EBUS-TBNA for the three groups were 87.04%, 89.55% and 90.70%, respectively, with malignant tumor diagnostic rates of 88.24%, 88.89% and 94.74%. No statistically significant differences were observed among the three groups (P>0.05). There were no instances of severe complications or adverse anesthesia reactions in any of the groups. Conclusion Compared to the combination of local anesthesia with intravenous analgesia and sedation, the implementation of EBUS-TBNA under general anesthesia, with or without ROSE, achieves equally accurate results, and general anesthesia combined with ROSE can reduce in the number of lymph node puncture needles. |
| first_indexed | 2024-03-07T13:58:25Z |
| format | Article |
| id | doaj.art-bb204ff5498b4b70b43543c883bec77b |
| institution | Directory Open Access Journal |
| issn | 1009-3419 1999-6187 |
| language | zho |
| last_indexed | 2024-03-07T13:58:25Z |
| publishDate | 2024-02-01 |
| publisher | Chinese Anti-Cancer Association; Chinese Antituberculosis Association |
| record_format | Article |
| series | Chinese Journal of Lung Cancer |
| spelling | doaj.art-bb204ff5498b4b70b43543c883bec77b2024-03-07T06:59:36ZzhoChinese Anti-Cancer Association; Chinese Antituberculosis AssociationChinese Journal of Lung Cancer1009-34191999-61872024-02-012729610110.3779/j.issn.1009-3419.2024.102.07Role of General Anesthesia and Rapid On-site Evaluation
in the Diagnosis of Lung Cancer with EBUS-TBNAYuhe HU0Yuying LI1Department of Respiratory and Critical Care Medicine, The Affiliated Hospital of Southwest Medical University,
Luzhou 646000, ChinaDepartment of Respiratory and Critical Care Medicine, The Affiliated Hospital of Southwest Medical University,
Luzhou 646000, ChinaBackground and objective Lung cancer is a common malignant tumor of respiratory system. Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a valuable tool for the diagnosis and staging of lung cancer. EBUS-TBNA is predominantly performed under local anesthesia or conscious sedation. However, the diagnostic performance of EBUS-TBNA under general anesthesia and in conjunction with rapid on-site evaluation (ROSE) remains uncertain. This study aims to investigate the value of general anesthesia and ROSE in the diagnosis of lung cancer with EBUS-TBNA. Methods A retrospective analysis was conducted on 164 patients treated in the Department of Respiratory and Critical Care Medicine of The Affiliated Hospital of Southwest Medical University from January 2018 to December 2022. All patients were preoperatively suspected of lung cancer and underwent EBUS-TBNA. Based on whether they received general anesthesia and ROSE, the patients were divided into three groups: local anesthesia group (LA group)(n=54), general anesthesia group (GA group)(n=67) and general anesthesia with ROSE group (GA-ROSE group)(n=43). The puncture characteristics and diagnostic differences were analyzed among the groups. Results The number of lymph node puncture needles in the LA group was higher than in GA-ROSE group (P<0.01). The overall diagnostic rates of EBUS-TBNA for the three groups were 87.04%, 89.55% and 90.70%, respectively, with malignant tumor diagnostic rates of 88.24%, 88.89% and 94.74%. No statistically significant differences were observed among the three groups (P>0.05). There were no instances of severe complications or adverse anesthesia reactions in any of the groups. Conclusion Compared to the combination of local anesthesia with intravenous analgesia and sedation, the implementation of EBUS-TBNA under general anesthesia, with or without ROSE, achieves equally accurate results, and general anesthesia combined with ROSE can reduce in the number of lymph node puncture needles.http://dx.doi.org/10.3779/j.issn.1009-3419.2024.102.07lung neoplasmsendobronchial ultrasound-guided transbronchial needle aspirationgeneral anesthesiarapid on-site evaluation |
| spellingShingle | Yuhe HU Yuying LI Role of General Anesthesia and Rapid On-site Evaluation in the Diagnosis of Lung Cancer with EBUS-TBNA Chinese Journal of Lung Cancer lung neoplasms endobronchial ultrasound-guided transbronchial needle aspiration general anesthesia rapid on-site evaluation |
| title | Role of General Anesthesia and Rapid On-site Evaluation
in the Diagnosis of Lung Cancer with EBUS-TBNA |
| title_full | Role of General Anesthesia and Rapid On-site Evaluation
in the Diagnosis of Lung Cancer with EBUS-TBNA |
| title_fullStr | Role of General Anesthesia and Rapid On-site Evaluation
in the Diagnosis of Lung Cancer with EBUS-TBNA |
| title_full_unstemmed | Role of General Anesthesia and Rapid On-site Evaluation
in the Diagnosis of Lung Cancer with EBUS-TBNA |
| title_short | Role of General Anesthesia and Rapid On-site Evaluation
in the Diagnosis of Lung Cancer with EBUS-TBNA |
| title_sort | role of general anesthesia and rapid on site evaluation
in the diagnosis of lung cancer with ebus tbna |
| topic | lung neoplasms endobronchial ultrasound-guided transbronchial needle aspiration general anesthesia rapid on-site evaluation |
| url | http://dx.doi.org/10.3779/j.issn.1009-3419.2024.102.07 |
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