THYMOMA (REVIEW OF THE LITERATURE)

Objective. We aimed to systematically review the literature dealing with the epidemiology, classification, clinical course, diagnosis and treatment of thymoma. Material and methods. We reviewed retrospective and prospective randomized trials using Medline and Elibrary databases. Results. The classif...

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Main Authors: O. A. Alexandrov, A. B. Ryabov, O. V. Pikin
格式: 文件
语言:Russian
出版: Russian Academy of Sciences, Tomsk National Research Medical Center 2017-09-01
丛编:Сибирский онкологический журнал
主题:
在线阅读:https://www.siboncoj.ru/jour/article/view/572
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author O. A. Alexandrov
A. B. Ryabov
O. V. Pikin
author_facet O. A. Alexandrov
A. B. Ryabov
O. V. Pikin
author_sort O. A. Alexandrov
collection DOAJ
description Objective. We aimed to systematically review the literature dealing with the epidemiology, classification, clinical course, diagnosis and treatment of thymoma. Material and methods. We reviewed retrospective and prospective randomized trials using Medline and Elibrary databases. Results. The classification system, prognostic factors, paraneoplastic syndromes and their incidence in patients with thyoma were described. The diagnostic value of computed tomography, magnetic resonance imaging and positron emission tomography was evaluated and the methods of morphologic verification were described. The main attention was paid to multimodality treatment of thymoma, including surgery and intraoperative radiotherapy. Conclusion. Thymoma is a rare tumor. The accumulation of long-term follow-up results prompted the changes in clinical management of thymoma. Predisposition to late recurrence even after radical surgery determined multimodality treatment strategies.
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spelling doaj.art-bb24d870b7c0494f8c33b901b75ed5402025-03-02T11:16:09ZrusRussian Academy of Sciences, Tomsk National Research Medical CenterСибирский онкологический журнал1814-48612312-31682017-09-01164768310.21294/1814-4861-2017-16-4-76-83470THYMOMA (REVIEW OF THE LITERATURE)O. A. Alexandrov0A. B. Ryabov1O. V. Pikin2Р.A. Herzen Moscow Oncology Research Institute – Branch of the National Medical Research Radiological Centre.Р.A. Herzen Moscow Oncology Research Institute – Branch of the National Medical Research Radiological Centre.Р.A. Herzen Moscow Oncology Research Institute – Branch of the National Medical Research Radiological Centre.Objective. We aimed to systematically review the literature dealing with the epidemiology, classification, clinical course, diagnosis and treatment of thymoma. Material and methods. We reviewed retrospective and prospective randomized trials using Medline and Elibrary databases. Results. The classification system, prognostic factors, paraneoplastic syndromes and their incidence in patients with thyoma were described. The diagnostic value of computed tomography, magnetic resonance imaging and positron emission tomography was evaluated and the methods of morphologic verification were described. The main attention was paid to multimodality treatment of thymoma, including surgery and intraoperative radiotherapy. Conclusion. Thymoma is a rare tumor. The accumulation of long-term follow-up results prompted the changes in clinical management of thymoma. Predisposition to late recurrence even after radical surgery determined multimodality treatment strategies.https://www.siboncoj.ru/jour/article/view/572thymomamediastinal tumorthymic tumor
spellingShingle O. A. Alexandrov
A. B. Ryabov
O. V. Pikin
THYMOMA (REVIEW OF THE LITERATURE)
Сибирский онкологический журнал
thymoma
mediastinal tumor
thymic tumor
title THYMOMA (REVIEW OF THE LITERATURE)
title_full THYMOMA (REVIEW OF THE LITERATURE)
title_fullStr THYMOMA (REVIEW OF THE LITERATURE)
title_full_unstemmed THYMOMA (REVIEW OF THE LITERATURE)
title_short THYMOMA (REVIEW OF THE LITERATURE)
title_sort thymoma review of the literature
topic thymoma
mediastinal tumor
thymic tumor
url https://www.siboncoj.ru/jour/article/view/572
work_keys_str_mv AT oaalexandrov thymomareviewoftheliterature
AT abryabov thymomareviewoftheliterature
AT ovpikin thymomareviewoftheliterature