Maternal to fetal transfer of vitamin C and vitamin E: effect on birth outcome in a Nigerian population
Background: New evidence suggests that excessive production of reactive oxygen species give rise to oxidative stress which could impair fetal growth. Antioxidant vitamin C and vitamin E have vital role in physiological process of pregnancy and health of the developing fetus. Aims and Objectives:...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Manipal College of Medical Sciences, Pokhara
2016-07-01
|
| Series: | Asian Journal of Medical Sciences |
| Subjects: | |
| Online Access: | https://www.nepjol.info/index.php/AJMS/article/view/14372 |
| Summary: | Background: New evidence suggests that excessive production of reactive oxygen species give rise to oxidative stress which could impair fetal growth. Antioxidant vitamin C and vitamin E have vital role in physiological process of pregnancy and health of the developing fetus.
Aims and Objectives: To determine the concentrations of vitamin C and vitamin E in pair-matched maternal and cord serum of newborns and to determine the relationship between maternal/cord serum vitamin C and vitamin E at delivery and birth outcomes.
Materials and Methods: A total of 209 maternal and cord blood samples were collected during delivery for serum vitamin C and E determination. Birth outcomes; birth weight, birth length, head circumference, and Apgar score were determined.
Result: Newborns had significantly higher levels of vitamin C as compared to their mothers, but had non-significant lower level of vitamin E. Levels of vitamin C and E in both maternal and cord serum were positively correlated to birth weight, birth length, head circumference and Apgar score.
Conclusion: Maternal vitamin C and E had significant effects on birth outcomes. A positive correlation of vitamin C and E indicates that their status in mother does influence newborns status. |
|---|---|
| ISSN: | 2467-9100 2091-0576 |