Maternal to fetal transfer of vitamin C and vitamin E: effect on birth outcome in a Nigerian population
Background: New evidence suggests that excessive production of reactive oxygen species give rise to oxidative stress which could impair fetal growth. Antioxidant vitamin C and vitamin E have vital role in physiological process of pregnancy and health of the developing fetus. Aims and Objectives:...
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| Format: | Article |
| Language: | English |
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Manipal College of Medical Sciences, Pokhara
2016-07-01
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| Series: | Asian Journal of Medical Sciences |
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| Online Access: | https://www.nepjol.info/index.php/AJMS/article/view/14372 |
| _version_ | 1818843340870778880 |
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| author | Ikechukwu Chidiebere Ikaraoha |
| author_facet | Ikechukwu Chidiebere Ikaraoha |
| author_sort | Ikechukwu Chidiebere Ikaraoha |
| collection | DOAJ |
| description | Background: New evidence suggests that excessive production of reactive oxygen species give rise to oxidative stress which could impair fetal growth. Antioxidant vitamin C and vitamin E have vital role in physiological process of pregnancy and health of the developing fetus.
Aims and Objectives: To determine the concentrations of vitamin C and vitamin E in pair-matched maternal and cord serum of newborns and to determine the relationship between maternal/cord serum vitamin C and vitamin E at delivery and birth outcomes.
Materials and Methods: A total of 209 maternal and cord blood samples were collected during delivery for serum vitamin C and E determination. Birth outcomes; birth weight, birth length, head circumference, and Apgar score were determined.
Result: Newborns had significantly higher levels of vitamin C as compared to their mothers, but had non-significant lower level of vitamin E. Levels of vitamin C and E in both maternal and cord serum were positively correlated to birth weight, birth length, head circumference and Apgar score.
Conclusion: Maternal vitamin C and E had significant effects on birth outcomes. A positive correlation of vitamin C and E indicates that their status in mother does influence newborns status. |
| first_indexed | 2024-12-19T04:56:19Z |
| format | Article |
| id | doaj.art-bb28e40ed38549f2bb5c562a4260251f |
| institution | Directory Open Access Journal |
| issn | 2467-9100 2091-0576 |
| language | English |
| last_indexed | 2024-12-19T04:56:19Z |
| publishDate | 2016-07-01 |
| publisher | Manipal College of Medical Sciences, Pokhara |
| record_format | Article |
| series | Asian Journal of Medical Sciences |
| spelling | doaj.art-bb28e40ed38549f2bb5c562a4260251f2022-12-21T20:35:13ZengManipal College of Medical Sciences, PokharaAsian Journal of Medical Sciences2467-91002091-05762016-07-01744954https://doi.org/10.3126/ajms.v7i4.14372Maternal to fetal transfer of vitamin C and vitamin E: effect on birth outcome in a Nigerian populationIkechukwu Chidiebere Ikaraoha 0Chemical Pathology Unit, Department of Medical Laboratory Science, Faculty of Health Science, Imo State University Owerri, Imo State http://orcid.org/0000-0003-0441-8693Background: New evidence suggests that excessive production of reactive oxygen species give rise to oxidative stress which could impair fetal growth. Antioxidant vitamin C and vitamin E have vital role in physiological process of pregnancy and health of the developing fetus. Aims and Objectives: To determine the concentrations of vitamin C and vitamin E in pair-matched maternal and cord serum of newborns and to determine the relationship between maternal/cord serum vitamin C and vitamin E at delivery and birth outcomes. Materials and Methods: A total of 209 maternal and cord blood samples were collected during delivery for serum vitamin C and E determination. Birth outcomes; birth weight, birth length, head circumference, and Apgar score were determined. Result: Newborns had significantly higher levels of vitamin C as compared to their mothers, but had non-significant lower level of vitamin E. Levels of vitamin C and E in both maternal and cord serum were positively correlated to birth weight, birth length, head circumference and Apgar score. Conclusion: Maternal vitamin C and E had significant effects on birth outcomes. A positive correlation of vitamin C and E indicates that their status in mother does influence newborns status.https://www.nepjol.info/index.php/AJMS/article/view/14372vitamin cvitamin eantioxidantmaternalnewbornbirth outcomenigeria |
| spellingShingle | Ikechukwu Chidiebere Ikaraoha Maternal to fetal transfer of vitamin C and vitamin E: effect on birth outcome in a Nigerian population Asian Journal of Medical Sciences vitamin c vitamin e antioxidant maternal newborn birth outcome nigeria |
| title | Maternal to fetal transfer of vitamin C and vitamin E: effect on birth outcome in a Nigerian population |
| title_full | Maternal to fetal transfer of vitamin C and vitamin E: effect on birth outcome in a Nigerian population |
| title_fullStr | Maternal to fetal transfer of vitamin C and vitamin E: effect on birth outcome in a Nigerian population |
| title_full_unstemmed | Maternal to fetal transfer of vitamin C and vitamin E: effect on birth outcome in a Nigerian population |
| title_short | Maternal to fetal transfer of vitamin C and vitamin E: effect on birth outcome in a Nigerian population |
| title_sort | maternal to fetal transfer of vitamin c and vitamin e effect on birth outcome in a nigerian population |
| topic | vitamin c vitamin e antioxidant maternal newborn birth outcome nigeria |
| url | https://www.nepjol.info/index.php/AJMS/article/view/14372 |
| work_keys_str_mv | AT ikechukwuchidiebereikaraoha maternaltofetaltransferofvitamincandvitamineeffectonbirthoutcomeinanigerianpopulation |