BCR-ABL affects STAT5A and STAT5B differentially.

Signal transducers and activators of transcription (STATs) are latent cytoplasmic transcription factors linking extracellular signals to target gene transcription. Hematopoietic cells express two highly conserved STAT5-isoforms (STAT5A/STAT5B), and STAT5 is directly activated by JAK2 downstream of s...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Michael Schaller-Schönitz, David Barzan, Andrew J K Williamson, John R Griffiths, Iris Dallmann, Karin Battmer, Arnold Ganser, Anthony D Whetton, Michaela Scherr, Matthias Eder
التنسيق: مقال
اللغة:English
منشور في: Public Library of Science (PLoS) 2014-01-01
سلاسل:PLoS ONE
الوصول للمادة أونلاين:http://europepmc.org/articles/PMC4023949?pdf=render