Vegetative plaque on the left superior eyelid
Abstract Herein we present case report of a 73‐year‐old female who developed a rapidly growing, ulcerated lesion on her left superior eyelid. Despite treatment for suspected infection, symptoms only marginally improved. Physical examination revealed a diffusely ulcerated multinodular tumour with ove...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2023-10-01
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| Series: | Skin Health and Disease |
| Online Access: | https://doi.org/10.1002/ski2.277 |
| _version_ | 1797666383132098560 |
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| author | Colin G. Wikholm Sach Thakker Pegah R. Bakhshi Adam J. Swigost Alan Moshell Michael A. Cardis |
| author_facet | Colin G. Wikholm Sach Thakker Pegah R. Bakhshi Adam J. Swigost Alan Moshell Michael A. Cardis |
| author_sort | Colin G. Wikholm |
| collection | DOAJ |
| description | Abstract Herein we present case report of a 73‐year‐old female who developed a rapidly growing, ulcerated lesion on her left superior eyelid. Despite treatment for suspected infection, symptoms only marginally improved. Physical examination revealed a diffusely ulcerated multinodular tumour with overlying haemorrhagic and serosanguineous exudate. A shave biopsy led to a diagnosis of primary cutaneous anaplastic large cell lymphoma (pcALCL), a rare CD30+ lymphoproliferative disorder. The patient had no extracutaneous involvement on PET‐CT and her prognosis is good given the indolent nature of pcALCL. Differential diagnoses included merkel cell carcinoma, periocular sebaceous carcinoma, lymphomatoid papulosis, and extranodal natural killer/T cell lymphoma. Prognosis for pcALCL is generally good. Treatment recommendation for pcALCL is surgical excision with negative margins for localised disease, while intravenous brentuximab vedotin is suggested for widespread, relapsed, and refractory disease. |
| first_indexed | 2024-03-11T19:57:48Z |
| format | Article |
| id | doaj.art-bb2d254e6486493589de4c011ef485de |
| institution | Directory Open Access Journal |
| issn | 2690-442X |
| language | English |
| last_indexed | 2024-03-11T19:57:48Z |
| publishDate | 2023-10-01 |
| publisher | Wiley |
| record_format | Article |
| series | Skin Health and Disease |
| spelling | doaj.art-bb2d254e6486493589de4c011ef485de2023-10-04T14:55:12ZengWileySkin Health and Disease2690-442X2023-10-0135n/an/a10.1002/ski2.277Vegetative plaque on the left superior eyelidColin G. Wikholm0Sach Thakker1Pegah R. Bakhshi2Adam J. Swigost3Alan Moshell4Michael A. Cardis5Department of Dermatology MedStar Washington Hospital Center / Georgetown University Hospital Washington Columbia USAGeorgetown University School of Medicine Washington Columbia USAGeorgetown University School of Medicine Washington Columbia USADepartment of Dermatology MedStar Washington Hospital Center / Georgetown University Hospital Washington Columbia USADepartment of Dermatology MedStar Washington Hospital Center / Georgetown University Hospital Washington Columbia USADepartment of Dermatology MedStar Washington Hospital Center / Georgetown University Hospital Washington Columbia USAAbstract Herein we present case report of a 73‐year‐old female who developed a rapidly growing, ulcerated lesion on her left superior eyelid. Despite treatment for suspected infection, symptoms only marginally improved. Physical examination revealed a diffusely ulcerated multinodular tumour with overlying haemorrhagic and serosanguineous exudate. A shave biopsy led to a diagnosis of primary cutaneous anaplastic large cell lymphoma (pcALCL), a rare CD30+ lymphoproliferative disorder. The patient had no extracutaneous involvement on PET‐CT and her prognosis is good given the indolent nature of pcALCL. Differential diagnoses included merkel cell carcinoma, periocular sebaceous carcinoma, lymphomatoid papulosis, and extranodal natural killer/T cell lymphoma. Prognosis for pcALCL is generally good. Treatment recommendation for pcALCL is surgical excision with negative margins for localised disease, while intravenous brentuximab vedotin is suggested for widespread, relapsed, and refractory disease.https://doi.org/10.1002/ski2.277 |
| spellingShingle | Colin G. Wikholm Sach Thakker Pegah R. Bakhshi Adam J. Swigost Alan Moshell Michael A. Cardis Vegetative plaque on the left superior eyelid Skin Health and Disease |
| title | Vegetative plaque on the left superior eyelid |
| title_full | Vegetative plaque on the left superior eyelid |
| title_fullStr | Vegetative plaque on the left superior eyelid |
| title_full_unstemmed | Vegetative plaque on the left superior eyelid |
| title_short | Vegetative plaque on the left superior eyelid |
| title_sort | vegetative plaque on the left superior eyelid |
| url | https://doi.org/10.1002/ski2.277 |
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