Preparation of aminoethyl glycosides for glycoconjugation

The synthesis of a number of aminoethyl glycosides of cell-surface carbohydrates, which are important intermediates for glycoarray synthesis, is described. A set of protocols was developed which provide these intermediates, in a short number of steps, from commercially available starting materials.

Bibliographic Details
Main Authors: Robert Šardzík, Gavin T. Noble, Martin J. Weissenborn, Andrew Martin, Simon J. Webb, Sabine L. Flitsch
Format: Article
Language:English
Published: Beilstein-Institut 2010-07-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.6.81
_version_ 1828928760337924096
author Robert Šardzík
Gavin T. Noble
Martin J. Weissenborn
Andrew Martin
Simon J. Webb
Sabine L. Flitsch
author_facet Robert Šardzík
Gavin T. Noble
Martin J. Weissenborn
Andrew Martin
Simon J. Webb
Sabine L. Flitsch
author_sort Robert Šardzík
collection DOAJ
description The synthesis of a number of aminoethyl glycosides of cell-surface carbohydrates, which are important intermediates for glycoarray synthesis, is described. A set of protocols was developed which provide these intermediates, in a short number of steps, from commercially available starting materials.
first_indexed 2024-12-14T00:08:58Z
format Article
id doaj.art-bb2d26b91a944e6fad871952ddf99b0d
institution Directory Open Access Journal
issn 1860-5397
language English
last_indexed 2024-12-14T00:08:58Z
publishDate 2010-07-01
publisher Beilstein-Institut
record_format Article
series Beilstein Journal of Organic Chemistry
spelling doaj.art-bb2d26b91a944e6fad871952ddf99b0d2022-12-21T23:25:51ZengBeilstein-InstitutBeilstein Journal of Organic Chemistry1860-53972010-07-016169970310.3762/bjoc.6.811860-5397-6-81Preparation of aminoethyl glycosides for glycoconjugationRobert Šardzík0Gavin T. Noble1Martin J. Weissenborn2Andrew Martin3Simon J. Webb4Sabine L. Flitsch5Manchester Interdisciplinary Biocentre & School of Chemistry, The University of Manchester, 131 Princess Street, Manchester, M1 7DN, UKManchester Interdisciplinary Biocentre & School of Chemistry, The University of Manchester, 131 Princess Street, Manchester, M1 7DN, UKManchester Interdisciplinary Biocentre & School of Chemistry, The University of Manchester, 131 Princess Street, Manchester, M1 7DN, UKManchester Interdisciplinary Biocentre & School of Chemistry, The University of Manchester, 131 Princess Street, Manchester, M1 7DN, UKManchester Interdisciplinary Biocentre & School of Chemistry, The University of Manchester, 131 Princess Street, Manchester, M1 7DN, UKManchester Interdisciplinary Biocentre & School of Chemistry, The University of Manchester, 131 Princess Street, Manchester, M1 7DN, UKThe synthesis of a number of aminoethyl glycosides of cell-surface carbohydrates, which are important intermediates for glycoarray synthesis, is described. A set of protocols was developed which provide these intermediates, in a short number of steps, from commercially available starting materials.https://doi.org/10.3762/bjoc.6.81aminoethyl glycosidesglycoarraysglycoconjugationglycosylation
spellingShingle Robert Šardzík
Gavin T. Noble
Martin J. Weissenborn
Andrew Martin
Simon J. Webb
Sabine L. Flitsch
Preparation of aminoethyl glycosides for glycoconjugation
Beilstein Journal of Organic Chemistry
aminoethyl glycosides
glycoarrays
glycoconjugation
glycosylation
title Preparation of aminoethyl glycosides for glycoconjugation
title_full Preparation of aminoethyl glycosides for glycoconjugation
title_fullStr Preparation of aminoethyl glycosides for glycoconjugation
title_full_unstemmed Preparation of aminoethyl glycosides for glycoconjugation
title_short Preparation of aminoethyl glycosides for glycoconjugation
title_sort preparation of aminoethyl glycosides for glycoconjugation
topic aminoethyl glycosides
glycoarrays
glycoconjugation
glycosylation
url https://doi.org/10.3762/bjoc.6.81
work_keys_str_mv AT robertsardzik preparationofaminoethylglycosidesforglycoconjugation
AT gavintnoble preparationofaminoethylglycosidesforglycoconjugation
AT martinjweissenborn preparationofaminoethylglycosidesforglycoconjugation
AT andrewmartin preparationofaminoethylglycosidesforglycoconjugation
AT simonjwebb preparationofaminoethylglycosidesforglycoconjugation
AT sabinelflitsch preparationofaminoethylglycosidesforglycoconjugation