Aggressiveness of non-EMT breast cancer cells relies on FBXO11 activity

Aggressiveness of non-EMT breast cancer cells relies on FBXO11 activity

Abstract Tumorigenesis is increasingly considered to rely on subclones of cells poised to undergo an epithelial to mesenchymal transition (EMT) program. We and others have provided evidence, however, that the tumorigenesis of human breast cancer is not always restricted to typical EMT cells but is a...

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Bibliographic Details
Main Authors: Sofie Otzen Bagger, Branden Michael Hopkinson, Deo Prakash Pandey, Mads Bak, Andreas Vincent Brydholm, Rene Villadsen, Kristian Helin, Lone Rønnov-Jessen, Ole William Petersen, Jiyoung Kim
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Molecular Cancer
Subjects:
Breast cancer
shRNA screening
Collective migration
Non-EMT
Online Access:http://link.springer.com/article/10.1186/s12943-018-0918-6

Internet

http://link.springer.com/article/10.1186/s12943-018-0918-6

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