Case Report: Pulmonary and Liver Sarcoidosis Suspected of Metastasis [version 2; referees: 2 approved]
Introduction: Sarcoidosis is a granulomatous disease with unknown cause that can vary from an asymptomatic condition. Almost half of the patients with sarcoidosis have no symptoms. In this article, we describe a sarcoidosis patient with lung and liver engagement; it may be confused with metastasis....
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| Format: | Article |
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F1000 Research Ltd
2018-06-01
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| Online Access: | https://f1000research.com/articles/7-288/v2 |
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| author | Behnam Jafari Gholamabas Sabz Elahe Masnavi Roghaye Panahi Saeid Jokar Amrollah Roozbehi Sajad Hasanzadeh |
| author_facet | Behnam Jafari Gholamabas Sabz Elahe Masnavi Roghaye Panahi Saeid Jokar Amrollah Roozbehi Sajad Hasanzadeh |
| author_sort | Behnam Jafari |
| collection | DOAJ |
| description | Introduction: Sarcoidosis is a granulomatous disease with unknown cause that can vary from an asymptomatic condition. Almost half of the patients with sarcoidosis have no symptoms. In this article, we describe a sarcoidosis patient with lung and liver engagement; it may be confused with metastasis. Case report: A 39-year-old man, with known as hypothyroidism who had come to the emergency ward with dyspnea and coughing after exposure to detergents in a closed environment. The patient smoked for 10 years (3 pack/year). No other findings were found in clinical examinations except for wheezing in the right lung. The patient's chest radiography was shown a mass. For further investigation, spiral CT scan was performed. Large lymph nodes on the right side of the trachea, measuring about 23 mm and a mass of 70 × 77 mm in the vicinity of the right lung hilum and a hypodense nodule in the posterior part of the liver with malignancy suspicious were reported. After several biopsy results was shown chronic granulomatous inflammation, the most important differential diagnosis is tuberculosis (TB) and sarcoidosis. Sputum smear, culture, and PCR were performed for tuberculosis. Also, the level of angiotensin-converting enzyme (ACE) was measured for sarcoidosis. the results ruled out TB and shown a higher level of ACE (ACE = 88 IU/L).After diagnosis treatment started with prednisolone. Now, the patient is in the follow- up. Conclusion: In hilar lymphadenopathy of lung sarcoidosis is the importance differential diagnosis that should be considered. |
| first_indexed | 2024-12-22T08:12:01Z |
| format | Article |
| id | doaj.art-bb377775e58d473fbb9a196dc0c0e2e5 |
| institution | Directory Open Access Journal |
| issn | 2046-1402 |
| language | English |
| last_indexed | 2024-12-22T08:12:01Z |
| publishDate | 2018-06-01 |
| publisher | F1000 Research Ltd |
| record_format | Article |
| series | F1000Research |
| spelling | doaj.art-bb377775e58d473fbb9a196dc0c0e2e52022-12-21T18:33:00ZengF1000 Research LtdF1000Research2046-14022018-06-01710.12688/f1000research.13787.216442Case Report: Pulmonary and Liver Sarcoidosis Suspected of Metastasis [version 2; referees: 2 approved]Behnam Jafari0Gholamabas Sabz1Elahe Masnavi2Roghaye Panahi3Saeid Jokar4Amrollah Roozbehi5Sajad Hasanzadeh6Student Research Committee, Yasuj University of Medical Sciences, Yasuj, IranDepartment of Obstetrics and Gynecology, Yasuj University of Medical Sciences, Yasuj, IranDepartment of Otolaryngology, Yasuj University of Medical Sciences, Yasuj, IranDepartment of Dental Medicine, Yasuj University of Medical Sciences, Yasuj, IranDepartment of Internal Medicine, Yasuj University of Medical Sciences, Yasuj, IranCellular and Molecular Research Center, Yasuj University of Medical Sciences, Yasuj, IranDepartment of Internal Medicine, Yasuj University of Medical Sciences, Yasuj, IranIntroduction: Sarcoidosis is a granulomatous disease with unknown cause that can vary from an asymptomatic condition. Almost half of the patients with sarcoidosis have no symptoms. In this article, we describe a sarcoidosis patient with lung and liver engagement; it may be confused with metastasis. Case report: A 39-year-old man, with known as hypothyroidism who had come to the emergency ward with dyspnea and coughing after exposure to detergents in a closed environment. The patient smoked for 10 years (3 pack/year). No other findings were found in clinical examinations except for wheezing in the right lung. The patient's chest radiography was shown a mass. For further investigation, spiral CT scan was performed. Large lymph nodes on the right side of the trachea, measuring about 23 mm and a mass of 70 × 77 mm in the vicinity of the right lung hilum and a hypodense nodule in the posterior part of the liver with malignancy suspicious were reported. After several biopsy results was shown chronic granulomatous inflammation, the most important differential diagnosis is tuberculosis (TB) and sarcoidosis. Sputum smear, culture, and PCR were performed for tuberculosis. Also, the level of angiotensin-converting enzyme (ACE) was measured for sarcoidosis. the results ruled out TB and shown a higher level of ACE (ACE = 88 IU/L).After diagnosis treatment started with prednisolone. Now, the patient is in the follow- up. Conclusion: In hilar lymphadenopathy of lung sarcoidosis is the importance differential diagnosis that should be considered.https://f1000research.com/articles/7-288/v2 |
| spellingShingle | Behnam Jafari Gholamabas Sabz Elahe Masnavi Roghaye Panahi Saeid Jokar Amrollah Roozbehi Sajad Hasanzadeh Case Report: Pulmonary and Liver Sarcoidosis Suspected of Metastasis [version 2; referees: 2 approved] F1000Research |
| title | Case Report: Pulmonary and Liver Sarcoidosis Suspected of Metastasis [version 2; referees: 2 approved] |
| title_full | Case Report: Pulmonary and Liver Sarcoidosis Suspected of Metastasis [version 2; referees: 2 approved] |
| title_fullStr | Case Report: Pulmonary and Liver Sarcoidosis Suspected of Metastasis [version 2; referees: 2 approved] |
| title_full_unstemmed | Case Report: Pulmonary and Liver Sarcoidosis Suspected of Metastasis [version 2; referees: 2 approved] |
| title_short | Case Report: Pulmonary and Liver Sarcoidosis Suspected of Metastasis [version 2; referees: 2 approved] |
| title_sort | case report pulmonary and liver sarcoidosis suspected of metastasis version 2 referees 2 approved |
| url | https://f1000research.com/articles/7-288/v2 |
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