The effect of MgO NPs that synthesis by Streptococcus spp. on immune system in rabbits
Abstract The current study describes a low-cost, environmentally friendly, and repeatable magnesium oxide nanoparticle manufacturing process mediated by Streptococcus spp. The UV spectrophotometer, Atomic Force Microscopy (AFM), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (...
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| Format: | Article |
| Language: | English |
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Faculty of Science, University of Kufa
2024-01-01
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| Series: | Magazin of Al-Kufa University for Biology |
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| Online Access: | https://journal.uokufa.edu.iq/index.php/ajb/article/view/13374 |
| _version_ | 1827314417954455552 |
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| author | Yousif M. Jebur Frial G. Abd |
| author_facet | Yousif M. Jebur Frial G. Abd |
| author_sort | Yousif M. Jebur |
| collection | DOAJ |
| description |
Abstract
The current study describes a low-cost, environmentally friendly, and repeatable magnesium oxide nanoparticle manufacturing process mediated by Streptococcus spp. The UV spectrophotometer, Atomic Force Microscopy (AFM), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), and Field Emission Scanning Electron Microscopy (FE-SEM) were all used to characterize the nanoparticles. The crystallographic cubic pattern seen by the XRD indicates that the structure of nanoparticles is mostly crystalline. The characterisation peaks and functional groups of MgO nanoparticles were identified using FTIR analysis. Furthermore, the study of MgO NPS produced by S. salivarius and S. mutans using field-emission scanning electron microscopy (FESEM) revealed that their average diameters were 49.85 nm and 66.15 nm, respectively. The findings of all immunological tests conducted in this investigation showed that MgO NPs produced by S. mutans and S. salivarius were substantially different from the control group (P 0.05) for systemic and mucosal antibody, respectively. In comparison to the control group, which had a mean value of (10)(1), MgO NPs biosynthesized from S. mutans and S. salivarius generated titers with mean values (1280)(2560) and (128)(256), respectively. In contrast to the control group, where the mitotic index resulted in a mean value of (3.56), the findings for the mitotic index were (10.16)(7.83). LIF in the test groups (51.33)(44.1) were significant compared to the control group (102.5).The MgO NPs elicited cellular immunity (delayed type hypersensitivity), which led to an increase in the spleen weight index in both test groups compared to the control.
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| first_indexed | 2024-04-24T22:34:37Z |
| format | Article |
| id | doaj.art-bb3ac1676e3346c7bc8f88ec432264a6 |
| institution | Directory Open Access Journal |
| issn | 2073-8854 2311-6544 |
| language | English |
| last_indexed | 2024-04-24T22:34:37Z |
| publishDate | 2024-01-01 |
| publisher | Faculty of Science, University of Kufa |
| record_format | Article |
| series | Magazin of Al-Kufa University for Biology |
| spelling | doaj.art-bb3ac1676e3346c7bc8f88ec432264a62024-03-19T12:39:00ZengFaculty of Science, University of KufaMagazin of Al-Kufa University for Biology2073-88542311-65442024-01-0115310.36320/ajb/v15.i3.13374The effect of MgO NPs that synthesis by Streptococcus spp. on immune system in rabbitsYousif M. Jebur0Frial G. Abd1Department of Ecology and Pollution, Faculty of Science, University of Kufa/ IraqDepartment of Ecology and Pollution, Faculty of Science, University of Kufa/ Iraq Abstract The current study describes a low-cost, environmentally friendly, and repeatable magnesium oxide nanoparticle manufacturing process mediated by Streptococcus spp. The UV spectrophotometer, Atomic Force Microscopy (AFM), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), and Field Emission Scanning Electron Microscopy (FE-SEM) were all used to characterize the nanoparticles. The crystallographic cubic pattern seen by the XRD indicates that the structure of nanoparticles is mostly crystalline. The characterisation peaks and functional groups of MgO nanoparticles were identified using FTIR analysis. Furthermore, the study of MgO NPS produced by S. salivarius and S. mutans using field-emission scanning electron microscopy (FESEM) revealed that their average diameters were 49.85 nm and 66.15 nm, respectively. The findings of all immunological tests conducted in this investigation showed that MgO NPs produced by S. mutans and S. salivarius were substantially different from the control group (P 0.05) for systemic and mucosal antibody, respectively. In comparison to the control group, which had a mean value of (10)(1), MgO NPs biosynthesized from S. mutans and S. salivarius generated titers with mean values (1280)(2560) and (128)(256), respectively. In contrast to the control group, where the mitotic index resulted in a mean value of (3.56), the findings for the mitotic index were (10.16)(7.83). LIF in the test groups (51.33)(44.1) were significant compared to the control group (102.5).The MgO NPs elicited cellular immunity (delayed type hypersensitivity), which led to an increase in the spleen weight index in both test groups compared to the control. https://journal.uokufa.edu.iq/index.php/ajb/article/view/13374Streptococcus spp. .MgO nanoparticles .Immune system.Streptococcus spp. |
| spellingShingle | Yousif M. Jebur Frial G. Abd The effect of MgO NPs that synthesis by Streptococcus spp. on immune system in rabbits Magazin of Al-Kufa University for Biology Streptococcus spp. .MgO nanoparticles .Immune system. Streptococcus spp. |
| title | The effect of MgO NPs that synthesis by Streptococcus spp. on immune system in rabbits |
| title_full | The effect of MgO NPs that synthesis by Streptococcus spp. on immune system in rabbits |
| title_fullStr | The effect of MgO NPs that synthesis by Streptococcus spp. on immune system in rabbits |
| title_full_unstemmed | The effect of MgO NPs that synthesis by Streptococcus spp. on immune system in rabbits |
| title_short | The effect of MgO NPs that synthesis by Streptococcus spp. on immune system in rabbits |
| title_sort | effect of mgo nps that synthesis by streptococcus spp on immune system in rabbits |
| topic | Streptococcus spp. .MgO nanoparticles .Immune system. Streptococcus spp. |
| url | https://journal.uokufa.edu.iq/index.php/ajb/article/view/13374 |
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