Reviewing the Role of the Efferent Vestibular System in Motor and Vestibular Circuits
Efferent circuits within the nervous system carry nerve impulses from the central nervous system to sensory end organs. Vestibular efferents originate in the brainstem and terminate on hair cells and primary afferent fibers in the semicircular canals and otolith organs within the inner ear. The func...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2017-08-01
|
| Series: | Frontiers in Physiology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/article/10.3389/fphys.2017.00552/full |
| _version_ | 1818657365872869376 |
|---|---|
| author | Miranda A. Mathews Aaron J. Camp Andrew J. Murray |
| author_facet | Miranda A. Mathews Aaron J. Camp Andrew J. Murray |
| author_sort | Miranda A. Mathews |
| collection | DOAJ |
| description | Efferent circuits within the nervous system carry nerve impulses from the central nervous system to sensory end organs. Vestibular efferents originate in the brainstem and terminate on hair cells and primary afferent fibers in the semicircular canals and otolith organs within the inner ear. The function of this efferent vestibular system (EVS) in vestibular and motor coordination though, has proven difficult to determine, and remains under debate. We consider current literature that implicate corollary discharge from the spinal cord through the efferent vestibular nucleus (EVN), and hint at a potential role in overall vestibular plasticity and compensation. Hypotheses range from differentiating between passive and active movements at the level of vestibular afferents, to EVS activation under specific behavioral and environmental contexts such as arousal, predation, and locomotion. In this review, we summarize current knowledge of EVS circuitry, its effects on vestibular hair cell and primary afferent activity, and discuss its potential functional roles. |
| first_indexed | 2024-12-17T03:40:20Z |
| format | Article |
| id | doaj.art-bb3b200721534ff08e9608d0a9df21df |
| institution | Directory Open Access Journal |
| issn | 1664-042X |
| language | English |
| last_indexed | 2024-12-17T03:40:20Z |
| publishDate | 2017-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Physiology |
| spelling | doaj.art-bb3b200721534ff08e9608d0a9df21df2022-12-21T22:05:01ZengFrontiers Media S.A.Frontiers in Physiology1664-042X2017-08-01810.3389/fphys.2017.00552280182Reviewing the Role of the Efferent Vestibular System in Motor and Vestibular CircuitsMiranda A. Mathews0Aaron J. Camp1Andrew J. Murray2Sensory Systems and Integration Laboratory, Bosch Institute, Discipline of Biomedical Science, University of SydneySydney, NSW, AustraliaSensory Systems and Integration Laboratory, Bosch Institute, Discipline of Biomedical Science, University of SydneySydney, NSW, AustraliaSainsbury Wellcome Centre for Neural Circuits and Behaviour, University College LondonLondon, United KingdomEfferent circuits within the nervous system carry nerve impulses from the central nervous system to sensory end organs. Vestibular efferents originate in the brainstem and terminate on hair cells and primary afferent fibers in the semicircular canals and otolith organs within the inner ear. The function of this efferent vestibular system (EVS) in vestibular and motor coordination though, has proven difficult to determine, and remains under debate. We consider current literature that implicate corollary discharge from the spinal cord through the efferent vestibular nucleus (EVN), and hint at a potential role in overall vestibular plasticity and compensation. Hypotheses range from differentiating between passive and active movements at the level of vestibular afferents, to EVS activation under specific behavioral and environmental contexts such as arousal, predation, and locomotion. In this review, we summarize current knowledge of EVS circuitry, its effects on vestibular hair cell and primary afferent activity, and discuss its potential functional roles.https://www.frontiersin.org/article/10.3389/fphys.2017.00552/fullefferent vestibular systemefferent vestibular nucleusEVSEVNcorollary dischargeVOR |
| spellingShingle | Miranda A. Mathews Aaron J. Camp Andrew J. Murray Reviewing the Role of the Efferent Vestibular System in Motor and Vestibular Circuits Frontiers in Physiology efferent vestibular system efferent vestibular nucleus EVS EVN corollary discharge VOR |
| title | Reviewing the Role of the Efferent Vestibular System in Motor and Vestibular Circuits |
| title_full | Reviewing the Role of the Efferent Vestibular System in Motor and Vestibular Circuits |
| title_fullStr | Reviewing the Role of the Efferent Vestibular System in Motor and Vestibular Circuits |
| title_full_unstemmed | Reviewing the Role of the Efferent Vestibular System in Motor and Vestibular Circuits |
| title_short | Reviewing the Role of the Efferent Vestibular System in Motor and Vestibular Circuits |
| title_sort | reviewing the role of the efferent vestibular system in motor and vestibular circuits |
| topic | efferent vestibular system efferent vestibular nucleus EVS EVN corollary discharge VOR |
| url | https://www.frontiersin.org/article/10.3389/fphys.2017.00552/full |
| work_keys_str_mv | AT mirandaamathews reviewingtheroleoftheefferentvestibularsysteminmotorandvestibularcircuits AT aaronjcamp reviewingtheroleoftheefferentvestibularsysteminmotorandvestibularcircuits AT andrewjmurray reviewingtheroleoftheefferentvestibularsysteminmotorandvestibularcircuits |