Recent Progress in Surface Plasmon Resonance Biosensors (2016 to Mid-2018)

More than 50 papers on surface plasmon resonance biosensors, published between 2016 and mid-2018, are reviewed. Papers concerning the determination of large particles such as vesicles, exosomes, cancer cells, living cells, stem cells, and microRNA are excluded, as these are covered by a very recent...

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Main Authors: Ewa Gorodkiewicz, Zenon Lukaszewski
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Biosensors
Subjects:
Online Access:https://www.mdpi.com/2079-6374/8/4/132
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author Ewa Gorodkiewicz
Zenon Lukaszewski
author_facet Ewa Gorodkiewicz
Zenon Lukaszewski
author_sort Ewa Gorodkiewicz
collection DOAJ
description More than 50 papers on surface plasmon resonance biosensors, published between 2016 and mid-2018, are reviewed. Papers concerning the determination of large particles such as vesicles, exosomes, cancer cells, living cells, stem cells, and microRNA are excluded, as these are covered by a very recent review. The reviewed papers are categorized into five groups, depending on the degree of maturity of the reported solution; ranging from simple marker detection to clinical application of a previously developed biosensor. Instrumental solutions and details of biosensor construction are analyzed, including the chips, receptors, and linkers used, as well as calibration strategies. Biosensors with a sandwich structure containing different nanoparticles are considered separately, as are SPR (Surface Plasmon Resonance) applications for investigating the interactions of biomolecules. An analysis is also made of the markers determined using the biosensors. In conclusion, there is shown to be a growing number of SPR applications in the solution of real clinical problems.
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spelling doaj.art-bb3b7572539449bbbc0c01100527ae082022-12-22T03:19:00ZengMDPI AGBiosensors2079-63742018-12-018413210.3390/bios8040132bios8040132Recent Progress in Surface Plasmon Resonance Biosensors (2016 to Mid-2018)Ewa Gorodkiewicz0Zenon Lukaszewski1Department of Electrochemistry, Institute of Chemistry, University of Bialystok, Ciolkowskiego 1K, 15-245 Bialystok, PolandFaculty of Chemical Technology, Poznan University of Technology, 60-965 Poznan, PolandMore than 50 papers on surface plasmon resonance biosensors, published between 2016 and mid-2018, are reviewed. Papers concerning the determination of large particles such as vesicles, exosomes, cancer cells, living cells, stem cells, and microRNA are excluded, as these are covered by a very recent review. The reviewed papers are categorized into five groups, depending on the degree of maturity of the reported solution; ranging from simple marker detection to clinical application of a previously developed biosensor. Instrumental solutions and details of biosensor construction are analyzed, including the chips, receptors, and linkers used, as well as calibration strategies. Biosensors with a sandwich structure containing different nanoparticles are considered separately, as are SPR (Surface Plasmon Resonance) applications for investigating the interactions of biomolecules. An analysis is also made of the markers determined using the biosensors. In conclusion, there is shown to be a growing number of SPR applications in the solution of real clinical problems.https://www.mdpi.com/2079-6374/8/4/132surface plasmon resonancecancer markersbiosensorsreceptor immobilizationantibodiesnanoparticles
spellingShingle Ewa Gorodkiewicz
Zenon Lukaszewski
Recent Progress in Surface Plasmon Resonance Biosensors (2016 to Mid-2018)
Biosensors
surface plasmon resonance
cancer markers
biosensors
receptor immobilization
antibodies
nanoparticles
title Recent Progress in Surface Plasmon Resonance Biosensors (2016 to Mid-2018)
title_full Recent Progress in Surface Plasmon Resonance Biosensors (2016 to Mid-2018)
title_fullStr Recent Progress in Surface Plasmon Resonance Biosensors (2016 to Mid-2018)
title_full_unstemmed Recent Progress in Surface Plasmon Resonance Biosensors (2016 to Mid-2018)
title_short Recent Progress in Surface Plasmon Resonance Biosensors (2016 to Mid-2018)
title_sort recent progress in surface plasmon resonance biosensors 2016 to mid 2018
topic surface plasmon resonance
cancer markers
biosensors
receptor immobilization
antibodies
nanoparticles
url https://www.mdpi.com/2079-6374/8/4/132
work_keys_str_mv AT ewagorodkiewicz recentprogressinsurfaceplasmonresonancebiosensors2016tomid2018
AT zenonlukaszewski recentprogressinsurfaceplasmonresonancebiosensors2016tomid2018