Recent Progress in Surface Plasmon Resonance Biosensors (2016 to Mid-2018)
More than 50 papers on surface plasmon resonance biosensors, published between 2016 and mid-2018, are reviewed. Papers concerning the determination of large particles such as vesicles, exosomes, cancer cells, living cells, stem cells, and microRNA are excluded, as these are covered by a very recent...
Main Authors: | , |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2018-12-01
|
Series: | Biosensors |
Subjects: | |
Online Access: | https://www.mdpi.com/2079-6374/8/4/132 |
_version_ | 1811263404549079040 |
---|---|
author | Ewa Gorodkiewicz Zenon Lukaszewski |
author_facet | Ewa Gorodkiewicz Zenon Lukaszewski |
author_sort | Ewa Gorodkiewicz |
collection | DOAJ |
description | More than 50 papers on surface plasmon resonance biosensors, published between 2016 and mid-2018, are reviewed. Papers concerning the determination of large particles such as vesicles, exosomes, cancer cells, living cells, stem cells, and microRNA are excluded, as these are covered by a very recent review. The reviewed papers are categorized into five groups, depending on the degree of maturity of the reported solution; ranging from simple marker detection to clinical application of a previously developed biosensor. Instrumental solutions and details of biosensor construction are analyzed, including the chips, receptors, and linkers used, as well as calibration strategies. Biosensors with a sandwich structure containing different nanoparticles are considered separately, as are SPR (Surface Plasmon Resonance) applications for investigating the interactions of biomolecules. An analysis is also made of the markers determined using the biosensors. In conclusion, there is shown to be a growing number of SPR applications in the solution of real clinical problems. |
first_indexed | 2024-04-12T19:44:34Z |
format | Article |
id | doaj.art-bb3b7572539449bbbc0c01100527ae08 |
institution | Directory Open Access Journal |
issn | 2079-6374 |
language | English |
last_indexed | 2024-04-12T19:44:34Z |
publishDate | 2018-12-01 |
publisher | MDPI AG |
record_format | Article |
series | Biosensors |
spelling | doaj.art-bb3b7572539449bbbc0c01100527ae082022-12-22T03:19:00ZengMDPI AGBiosensors2079-63742018-12-018413210.3390/bios8040132bios8040132Recent Progress in Surface Plasmon Resonance Biosensors (2016 to Mid-2018)Ewa Gorodkiewicz0Zenon Lukaszewski1Department of Electrochemistry, Institute of Chemistry, University of Bialystok, Ciolkowskiego 1K, 15-245 Bialystok, PolandFaculty of Chemical Technology, Poznan University of Technology, 60-965 Poznan, PolandMore than 50 papers on surface plasmon resonance biosensors, published between 2016 and mid-2018, are reviewed. Papers concerning the determination of large particles such as vesicles, exosomes, cancer cells, living cells, stem cells, and microRNA are excluded, as these are covered by a very recent review. The reviewed papers are categorized into five groups, depending on the degree of maturity of the reported solution; ranging from simple marker detection to clinical application of a previously developed biosensor. Instrumental solutions and details of biosensor construction are analyzed, including the chips, receptors, and linkers used, as well as calibration strategies. Biosensors with a sandwich structure containing different nanoparticles are considered separately, as are SPR (Surface Plasmon Resonance) applications for investigating the interactions of biomolecules. An analysis is also made of the markers determined using the biosensors. In conclusion, there is shown to be a growing number of SPR applications in the solution of real clinical problems.https://www.mdpi.com/2079-6374/8/4/132surface plasmon resonancecancer markersbiosensorsreceptor immobilizationantibodiesnanoparticles |
spellingShingle | Ewa Gorodkiewicz Zenon Lukaszewski Recent Progress in Surface Plasmon Resonance Biosensors (2016 to Mid-2018) Biosensors surface plasmon resonance cancer markers biosensors receptor immobilization antibodies nanoparticles |
title | Recent Progress in Surface Plasmon Resonance Biosensors (2016 to Mid-2018) |
title_full | Recent Progress in Surface Plasmon Resonance Biosensors (2016 to Mid-2018) |
title_fullStr | Recent Progress in Surface Plasmon Resonance Biosensors (2016 to Mid-2018) |
title_full_unstemmed | Recent Progress in Surface Plasmon Resonance Biosensors (2016 to Mid-2018) |
title_short | Recent Progress in Surface Plasmon Resonance Biosensors (2016 to Mid-2018) |
title_sort | recent progress in surface plasmon resonance biosensors 2016 to mid 2018 |
topic | surface plasmon resonance cancer markers biosensors receptor immobilization antibodies nanoparticles |
url | https://www.mdpi.com/2079-6374/8/4/132 |
work_keys_str_mv | AT ewagorodkiewicz recentprogressinsurfaceplasmonresonancebiosensors2016tomid2018 AT zenonlukaszewski recentprogressinsurfaceplasmonresonancebiosensors2016tomid2018 |