Intelligent tunable CAR-T cell therapy leads the new trend

Adoptive transfer of T cells engineered with chimeric antigen receptor (CAR) has been proved to have robust anti-tumor effects against hematological malignancies. However, problems about safety and efficacy, such as cytokine release syndrome (CRS), T cell exhaustion and antigen escape are still rais...

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Bibliographic Details
Main Authors: Jiayi Cheng, Mingyao Liu, Jiqin Zhang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2023-12-01
Series:Synthetic and Systems Biotechnology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405805X23000753